Ryo Konno

INTRODUCTION: Endometriosis-associated intestinal tumors (EAITs) are rare malignancies that arise from ectopic endometrial tissue, and their clinical and molecular characteristics remain poorly defined. CASE PRESENTATION: We report a 53-ye…

STUDY OBJECTIVE: To investigate the feasibility of magnetic resonance imaging (MRI) in detecting and classifying adhesions between pelvic organs caused by endometriosis, comparing MRI findings to those obtained by laparoscopy. DESIGN: Pros…

Current pharmacological treatments for endometriosis are limited to hormonal agents that can relieve pain but cannot cure the disease. Therefore, the development of a disease-modifying drug for endometriosis is an unmet medical need. By stu…

STUDY QUESTION: Does spontaneous endometriosis in cynomolgus monkeys have the characteristics required of a good experimental model? SUMMARY ANSWER: Spontaneous endometriosis in cynomolgus monkeys exhibited similar clinicopathological chara…

Primary umbilical endometriosis is extremely rare, although cases secondary to previous surgery have occasionally been reported. Here, we report three cases of umbilical endometriosis: two cases with previous cesarean section and one case o…

PROBLEM: To investigate the molecular mechanism of endometriosis, gene expression profiling was analyzed in a rat endometriosis model. METHOD OF STUDY: An endometriosis model was induced by uterine autotransplantation in the peritoneal cavi…

OBJECTIVE: To investigate the localization of the proteins osteopontin (OPN) and L-selectin (SELL). DESIGN: Retrospective nonrandomized immunohistochemical study in a surgically induced rat model of peritoneal endometriosis and in samples …

PROBLEM: Although the presence of mast cells in endometriosis lesions has been reported, there have been no reports of their pathological localization in ovarian endometrial cysts. METHODS OF STUDY: The localization of mast cells in ovaria…