Ayako Nishimoto

ORCID: 0000-0002-8654-7423 · 7 papers in corpus
other 2025
Scientific reports ·doi:10.1038/s41598-025-30277-x

Diagnosis of endometriosis faces significant challenges including diagnostic delay and reliance on invasive procedures. Deep endometriosis (DE) poses additional difficulties in non-invasive diagnosis due to its subtle and complex imaging fe…

2025
Scientific reports ·doi:10.1038/s41598-025-88022-3

Postoperative adhesions frequently occur following abdominal surgical interventions, leading to serious morbidities and requiring new therapeutic strategies. The development of new therapeutic agents to reduce postoperative adhesions needs …

other 2025
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2025.114756

STUDY OBJECTIVE: To investigate the feasibility of magnetic resonance imaging (MRI) in detecting and classifying adhesions between pelvic organs caused by endometriosis, comparing MRI findings to those obtained by laparoscopy. DESIGN: Pros…

other 2025
F&S reports ·doi:10.1016/j.xfre.2025.04.009

OBJECTIVE: To evaluate the safety and pharmacokinetics/pharmacodynamics of AMY109, an anti-interleukin-8 recycling antibody in a first-in-human phase 1 trial in healthy volunteers (HVs) and patients with endometriosis. DESIGN: A multicente…

article 2023
Science translational medicine ·doi:10.1126/scitranslmed.abq5858

Current pharmacological treatments for endometriosis are limited to hormonal agents that can relieve pain but cannot cure the disease. Therefore, the development of a disease-modifying drug for endometriosis is an unmet medical need. By stu…

article 2018
Human Reproduction ·doi:10.1093/humrep/dey095

STUDY QUESTION: Does spontaneous endometriosis in cynomolgus monkeys have the characteristics required of a good experimental model? SUMMARY ANSWER: Spontaneous endometriosis in cynomolgus monkeys exhibited similar clinicopathological chara…

other 2016
Human Reproduction ·doi:10.1093/humrep/dew209

STUDY QUESTION: What are the characteristics of spontaneous endometriosis in cynomolgus monkeys? SUMMARY ANSWER: Spontaneous endometriosis in cynomolgus monkeys exhibited similar characteristics to the human disease. WHAT IS KNOWN ALREADY…