Ocktariyana Ocktariyana

Endometriosis is a common benign gynecological disease characterized by the ectopic growth of endometrial tissue. Its pathogenesis is influenced by complex genetic and epigenetic factors, making diagnosis and treatment challenging. This stu…

Endometriosis is a gynecological condition characterized by the development of endometrial tissue outside the uterus, often leading to pain and infertility. We explore the relationship between endometriosis and the effects of DNA methylatio…

Transient Receptor Ankyrin Member 1 (TRPA1) is an ion channel family protein that regulates pain sensation through sensory neurons' activity. This study's purpose to analyzes the DNA methylation and mRNA expression level of the TRPA1 gene i…

OBJECTIVE: Endometriosis is a multifactorial disease that affects 10% of women of childbearing age. Its development is known to be related to the MMP-2 gene. Specifically, the expression of MMP-2 is increase in endometriosis. The aim of thi…

Abstract It has been known that the EGFR have the role for regulation the cytoskeleton activity and its expression increased in endometriosis tissue. The aim of this study was to evaluate the DNA methylation of the EGFR gene that might caus…

Focal adhesion molecules involve in cellular migration, attachment, and play a role in endometriosis pathomechanisms. Recent studies showed that the expression of RAC1, a gene encoded focal adhesion molecule, was predominantly found in endo…

Abstract Endometriosis is a common, benign, oestrogen-dependent, chronic gynaecological disorder associated with pelvic pain and infertility. Increasing of P2X3 receptors induced sensitization of pain in endometriosis patients. Epigenetic m…