Reinaldo González-Ramos

No ORCID on file · 17 papers in corpus · active 2007-2017

Study types

  • article 14
  • review 3

Condition tags

  • endometriosis 16
  • mesh:D004715 12
  • infertility 3
  • chronic_pelvic_pain 1
article 2017
hCG activates Epac-Erk1/2 signaling regulating Progesterone Receptor expression and function in human endometrial stromal cells
·doi:10.1093/molehr/gax015

STUDY QUESTION: How does hCG signal in human endometrial stromal cells (ESCs) and what is its role in regulating ESC function? SUMMARY ANSWER: hCG signaling in ESCs activates the extracellular signal-regulated protein kinases 1 and 2 (Erk1/…

article 2016
Endometrial expression and in vitro modulation of the iron transporter divalent metal transporter-1: implications for endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.04.002
article 2015
Differential expression of upstream stimulatory factor (USF) 2 variants in eutopic endometria from women with endometriosis: estradiol regulation
Biological research ·doi:10.1186/s40659-015-0047-2

BACKGROUND: Endometriosis, pro-inflammatory and invasive benign disease estrogen dependent, abnormally express in endometria the enzyme P450Arom, positively regulated by steroid factor-1 (SF-1). Our objective was to study the nuclear protei…

article 2015
Nerve Fibres Detection in Paired Eutopic and Ectopic Endometria from Women with Endometriosis: Correlation with Nerve Growth Factor Expression
·doi:10.4236/ojog.2015.57060

Endometriosis, disorder characterized by the presence of endometrium outside the uterus cavity, is associated with chronic pelvic pain. Nerve growth factor (NGF) participates in development, repair and survival of neurons. We evaluated NGF …

article 2014
Iron overload–modulated nuclear factor kappa-B activation in human endometrial stromal cells as a mechanism postulated in endometriosis pathogenesis
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.10.046
review 2012
Nuclear factor-kappaB: a main regulator of inflammation and cell survival in endometriosis pathophysiology
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.06.021

OBJECTIVE: To update, analyze, and summarize the literature concerning nuclear factor-kappaB (NF-κB) participation in endometriosis pathophysiology. DESIGN: Review. RESULT(S): Nuclear factor-kappaB is physiologically activated in the huma…

review 2011
Insights into iron and nuclear factor-kappa B (NF-kappaB) involvement in chronic inflammatory processes in peritoneal endometriosis.
Histology and histopathology ·doi:10.14670/hh-26.1083

Endometriosis is a chronic pelvic inflammatory process. Local inflammation is known to play a role in pain and infertility associated with the disease, and may be extensively involved in molecular and cellular processes leading to endometri…

article 2011
Insights into iron and nuclearfactor-kappa B (NF-κB) involvement in chronicinflammatory processes in peritoneal endometriosis
article 2011
Physiologic activation of nuclear factor kappa-B in the endometrium during the menstrual cycle is altered in endometriosis patients
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.12.006
review 2010
Involvement of the nuclear factor-κB pathway in the pathogenesis of endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.01.013
article 2010
Posters * Endometriosis, Endometrium and Implantation
·doi:10.1093/humrep/de.25.s1.242

Introduction: Endometriosis, defined as the growth of endometrial tissue outside \nthe uterine cavity is a common gynaecological disorder affecting 10-15% \nof women in their reproductive years. It is a major clinical problem causing in- \n…

article 2008
CONSTITUTIVE ACTIVATION OF THE TRANSCRIPTION FACTOR NUCLEAR FACTOR-KAPPAB (NF-KAPPAB) IN THE ENDOMETRIUM OF PATIENTS WITH ENDOMETRIOSIS. ROLE OF IRON IN THE MOLECULAR PHYSIOPATHOLOGY OF ENDOMETRIOSIS
article 2008
Iron storage is significantly increased in peritoneal macrophages of endometriosis patients and correlates with iron overload in peritoneal fluid
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.02.103
article 2008
Unsuccessful Induction of Endometriosis in Female Rhesus Macaques (Macaca mulatta)
Gynecologic and obstetric investigation ·doi:10.1159/000127447

BACKGROUND/AIMS: The aim of this study was to induce endometriosis in female rhesus macaques (Macaca mulatta) for research purposes. METHODS: Three female monkeys from 4 to 4.5 years of age underwent three consecutive attempts at endometrio…

article 2007
Agents Blocking the Nuclear Factor-κB Pathway Are Effective Inhibitors of Endometriosis in an in vivo Experimental Model
Gynecologic and obstetric investigation ·doi:10.1159/000111148

BACKGROUND: In vitro studies suggest that the transcription factor nuclear factor-kappa B (NF-kappaB) is implicated in the transduction of proinflammatory signals in endometriosis. The aim of this study was to investigate the involvement of…

article 2007
Increased activation of nuclear factor-kappa B (NF-κB) in isolated peritoneal macrophages of patients with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.06.015
article 2007
Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis
Molecular human reproduction ·doi:10.1093/molehr/gam033

Red (active), black and white endometriotic lesions are characteristic of peritoneal endometriosis. The transcription factor nuclear factor-kappa B (NF-kappaB) activates proinflammatory, proliferative and antiapoptotic genes in many cell ty…