Jacques Donnez
ORCID: 0000-0003-2528-206X
· 266 papers in corpus
2001
Objective To evaluate the prevalence of ureteral endometriosis and to describe the laparoscopic surgery. Design This is a prospective study. Results In a series of 306 patients with rectovaginal adenomyotic nodules, preoperative intravenous…
lab-animal
2000
OBJECTIVE: To evaluate the implantation of menstrual endometrium and the early stages of evolution of endometriotic lesions. DESIGN: Experimental prospective study. SETTING: An academic research environment. ANIMALS: Ten nude mice. INTE…
2000
other
2000
other
2000
lab-animal
2000
OBJECTIVE: To investigate the regulation of perimenstrual MMP-1 expression in human endometrium. DESIGN: In vitro study utilizing epithelial-stromal co-cultures. SETTING: Cell Biology Unit, International Institute of Cellular and Molecula…
lab-animal
2000
The objective of this study was to analyse the histological and immunohistochemical characteristics of cultured explants of human endometrium transplanted into nude mice. Biopsies of eutopic endometrium were taken from six patients during l…
1999
review
1999
OBJECTIVE: To provide an overview of the medical, surgical and combined therapy options for endometriosis. RESULTS: Available medical options include danazol, progestogens, gestrinone, oral contraceptive agents, analgesics and gonadotropin…
1998
Objective: Laparoscopic procedure with excision of deep fibrotic\nendometriotic nodules of the rectovaginal septum and histological\nstudy of the lesions. \nSetting:\nAn academic teaching hospital.\nPatients: A series of 500 patients underw…
1998
peer reviewed
1998
other
1997
OBJECTIVE: To determine whether interstitial collagenase (matrix metalloproteinase-1), known to play a pivotal role in the initiation of menstruation, contributes to the pathogenesis of endometriosis. DESIGN: Serial sections of peritoneal …
rct
1997
OBJECTIVE: To confirm the advantages of goserelin prior to endometrial ablation for the treatment of dysfunctional uterine bleeding. DESIGN: Multicenter, prospective, randomized, double-blind study. PATIENT(S): Cycling premenopausal women…
observational
1997
OBJECTIVE: To assess the proliferative activity of eutopic and ectopic endometrium throughout the menstrual cycle and its correlation to steroid receptor content. DESIGN: The immunohistochemical use of Ki 67 was applied to investigate the …
1997
In the pelvis, three different forms of endometriosis must be considered: 1) peritoneal endometriosis; 2) ovarian endometriosis and 3) rectovaginal septum endometriosis.
1997
ObjectiveTo compare the localization of adhesion proteins (laminin and fibronectin) and their receptors of the integrin family in endometriosis and endometrium.DesignAn immunohistochemical study.SettingUniversity Hospital, Department of Gyn…
1997
Morphological and morphometric data showed similarities between eutopic endometrium and red peritoneal lesions, suggesting that these lesions are the first stage of early implantation of endometrial glands and stroma. An inflammatory reacti…
review
1997
OBJECTIVE: To review the histogenesis of peritoneal, ovarian, and rectovaginal endometriotic lesions. DESIGN: The comparison of morphologic, morphometric, and histochemical data observed in each type of lesion. SETTING: A university hospi…
other
1997
OBJECTIVE: Laparoscopic procedure with excision of deep fibrotic endometriotic nodules of the rectovaginal septum and histological study of the lesions. SETTING: An academic teaching hospital. PARTICIPANTS: A series of 500 women undergoin…
1996
other
1996
Recent studies suggest that interstitial collagenase (MMP-1) is an essential enzyme in the early events leading to menstruation. This study analyses its cellular origin, regulation and relation to extracellular matrix breakdown in the human…
other
1996
The management of large endometriomas was described in a series of 814 patients. Combined therapy using gonadotrophin-releasing hormone agonist (GnRHa) and carbon dioxide laser laparoscopy was proposed. Drainage and GnRHa for 12 weeks provo…
review
1996
This is a color-illustrated advanced clinical monograph that analyzes and compares the three forms of endometriosis: peritoneal, ovarian, and rectovaginal. Three core chapters cover the histopathology of peritoneal endometriosis, ovarian en…
lab-animal
1996
Collagenases are the only mammalian enzymes able to cleave, at neutral pH, the triple helical domain of fibrillar collagens, major constituents of the extracellular matrix of the endometrium. Interstitial collagenase is expressed, secreted …