Lin W

ORCID: 0000-0002-2940-6966 · 33 papers in corpus
rct 2026
Journal of clinical monitoring and computing ·doi:10.1007/s10877-026-01452-w

This study aimed to achieve two primary objectives: (1) to evaluate the opioid-sparing effect of Surgical Pleth Index (SPI)-directed analgesia during surgery via a randomized controlled trial (RCT), and (2) to propose and preliminarily asse…

observational 2026
Annals of diagnostic pathology ·doi:10.1016/j.anndiagpath.2025.152534

This study aimed to evaluate the clinicopathological features of ovarian seromucinous borderline tumors (SMBTs) and mucinous borderline tumors (MBTs) and to establish a diagnostic approach using immunohistochemistry (IHC) and Alcian Blue-Pe…

2026
Gynecology and Minimally Invasive Therapy
observational 2026
Annals of medicine ·doi:10.1080/07853890.2026.2620857

PURPOSE: Adenomyosis (AM) with dysmenorrhea (AMD) is a global public health concern that may involve abnormal brain function and heightened vulnerability to anxiety and depression. This study aimed to investigate static and dynamic regional…

lab-animal 2026
Nature communications ·doi:10.1038/s41467-026-71140-5

Acute pancreatitis is a complex inflammatory disease with high morbidity and mortality, closely associated with intestinal barrier dysfunction, gut microbiota dysbiosis and abnormal lipid metabolism. Akkermansia muciniphila has been shown t…

observational 2026
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01522-9

BACKGROUND: Ovarian endometrioma (OMA) is the most prevalent form of endometriosis. Conservative surgical management of the condition is associated with a relatively high recurrence rate, the degree of which is potentially linked to disease…

diagnostic-accuracy 2026
Quantitative Imaging in Medicine and Surgery ·doi:10.21037/qims-2025-1-2754

BackgroundThe Ovarian-Adnexal Reporting and Data System (O-RADS) ultrasound (US) is a standardized tool for assessing adult adnexal lesions, but its performance in the pediatric population has not been fully validated. This study aimed to v…

other 2025
Scientific reports ·doi:10.1038/s41598-025-19007-5

Endometriosis (EMs) is a chronic disease affecting millions of women worldwide, yet its pathogenesis remains unclear, and current diagnostic methods are limited. This study based on the EMs dataset from Gene Expression Omnibus (GEO), key ge…

review 2025
Frontiers in pain research (Lausanne, Switzerland) ·doi:10.3389/fpain.2025.1544909

OBJECTIVES: The review aimed to evaluate the efficacy of pulsed radiofrequency (PRF) in treating chronic pain by analyzing recent literature. STUDY DESIGN: This is a narrative review of relevant articles on the effectiveness of PRF for chr…

observational 2025
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-025-03573-8

PURPOSE: To evaluate whether prior SARS-CoV-2 infection adversely affects live birth and perinatal outcomes following subsequent frozen-thawed embryo transfer (FET) and to further investigate whether the time interval between infection and …

case-report 2025
International journal of surgery case reports ·doi:10.1016/j.ijscr.2025.112106

INTRODUCTION: Mesonephric-like adenocarcinoma (MLA) is a recently recognized, rare subtype of endometrial carcinoma that can also arise in the ovary. Ovarian MLA is uncommon and often misdiagnosed due to its varied growth patterns and overl…

review 2025
Human genomics ·doi:10.1186/s40246-025-00741-w

Female adnexal malignancies, while relatively uncommon, exhibit high mortality rates due to often-late diagnosis. The serine/threonine kinase 11 (STK11) is a tumor suppressor gene, and its inactivation or mutation often leads to an autosoma…

observational 2024
·doi:10.21203/rs.3.rs-3806951/v1

Abstract Endometriosis is an inflammation-associated disease, primarily but not always associated with abnormal immune system function and expression of immune factors. The microbiota of the female reproductive tract, including the vagina …

other 2024
Journal of cancer research and clinical oncology ·doi:10.1007/s00432-024-05872-6

PURPOSE: To develop a deep learning (DL) model for differentiating between benign and malignant ovarian tumors of Ovarian-Adnexal Reporting and Data System Ultrasound (O-RADS US) Category 4 lesions, and validate its diagnostic performance. …

diagnostic-accuracy 2024
BMC pediatrics ·doi:10.1186/s12887-024-04704-3

BACKGROUND: Neonatal respiratory distress syndrome (NRDS) is a prevalent cause of respiratory failure and death among newborns, and prompt diagnosis is imperative. Historically, diagnosis of NRDS relied mostly on typical clinical manifestat…

lab-animal 2024
Molecular medicine (Cambridge, Mass.) ·doi:10.1186/s10020-023-00763-x

BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. The sex differences in the occurrence and fatality rates of non-small cell lung cancer (NSCLC), along with its association with estrogen dependence, suggest tha…

observational 2024
Environment & health (Washington, D.C.) ·doi:10.1021/envhealth.4c00107

The adverse effect of ambient PM2.5 exposure on very early pregnancy (VEP) remains controversial among epidemiological studies but is supported by toxicological evidence. We adopted a multicenter retrospective cohort of 141,040 cycles to ev…

other 2024
BMC pregnancy and childbirth ·doi:10.1186/s12884-023-06205-0

PURPOSE: Since the unexplained in vitro fertilization failure occurs frequently, it is of great importance and clinical value to identify potential underlying predictors. This study aimed to explore whether the percentage of sperm with a sm…

other 2023
Frontiers in medicine ·doi:10.3389/fmed.2023.1138690

BACKGROUND: Ovary is a common organ site involved by endometriosis. We previously found that fallopian tube may contribute to the histogenesis of ovarian endometriosis. The finding was novel and requires further studies. We addressed this i…

case-report 2022
Current medical imaging ·doi:10.2174/1573405618666220615161300

INTRODUCTION: Extrauterine endometrial stromal sarcoma (EESS) arising from Deep pelvic endometriosis (DPE) has a poor life quality and is difficult to diagnose pre-operatively. However, the patient's quality of life can be improved when it …

other 2022
Frontiers in genetics ·doi:10.3389/fgene.2022.996310

Objective: Pelvic organ prolapse (POP) affects a large proportion of adult women, but the pathogenesis of POP remains unclear. The increase in global population aging will impose a substantial medical burden. Herein, we aimed to explore the…

lab-animal 2022
The EMBO journal ·doi:10.15252/embj.2021110218

Carnitine metabolism is thought to be negatively correlated with the progression of hepatocellular carcinoma (HCC) and the specific molecular mechanism is yet to be fully elucidated. Here, we report that little characterized cysteine-rich p…

lab-animal 2021
Frontiers in veterinary science ·doi:10.3389/fvets.2021.659840

Background: Avian leukosis virus subgroup J (ALV-J) is an oncogenic virus that causes serious economic losses in the poultry industry; unfortunately, there is no effective vaccine against ALV-J. DNA methylation plays a crucial role in sever…

2021
·doi:10.21203/rs.3.rs-746595/v1

Abstract Background Ovary is the most common organ site involved by endometriosis. We previously found that fallopian tube may contribute to the histogenesis of ovarian endometriosis. The finding was novel and requires further studies. We …

observational 2020
American journal of cancer research ·doi:10.21203/rs.3.rs-39624/v1

Recent advances suggest the fallopian tube as the main anatomic site for high-grade ovarian or pelvic serous carcinoma (O/PSC). Many studies on the biologic role of tubal secretory cells in O/PSC development has been performed in the last d…