Ricardo H. Asch — Endo Lab

other 1984

Etiology of infertility in monkeys with endometriosis: luteinized unruptured follicles, luteal phase defects, pelvic adhesions, and spontaneous abortions

Fertility and Sterility ·doi:10.1016/s0015-0282(16)47552-7

To elucidate the etiology of infertility due to endometriosis, we autografted endometrial or adipose tissue to the pelvic peritoneum of 21 cynomolgus monkeys. These primates were divided into five groups: control animals with adipose tissue…

article 1984

Etiology of infertility in monkeys with endometriosis: Measurement of peritoneal fluid prostaglandins

American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(84)80136-2

To study the relationship between peritoneal fluid prostaglandins and infertility associated with endometriosis, we autografted endometrial or adipose tissue to the pelvic peritoneum in 21 monkeys. Peritoneal washings were collected prior t…

article 1980

Danazol binding and translocation of steroid receptors

·doi:10.1016/0002-9378(80)90665-1

Danazol, an isoxazol derivative of ethinyl testosterone which suppresses gonadotropin levels and acts as a weak androgen, is shown by competition studies to bind rat androgen receptor (Ki 10(-8M) and progestin receptor (Ki 10(-7)M) but not …

article 1980

Danazol for benign breast disease

·doi:10.1016/0002-9378(80)90704-8

Three groups of women with benign breast disease were treated with danazol for 3 to 6 months. Doses of 100 mg per day were given to 40 patients, 200 mg to 55, and 400 mg to 35. The age range of the patients was 20 to 48 years. The patients …

article 1980

Mechanism of induction of luteal phase defects by danazol

·doi:10.1016/0002-9378(80)91054-6

The effects of danazol on the luteal phase of cycling rhesus monkeys and on the ability of the intact rhesus monkey to respond to hCG stimulation were studied in two experiments. In a third experiment the impact of danazol upon the response…

article 1980

Surgical Induction of Endometriosis in the Rabbit: Effects on Fertility and Concentrations of Peritoneal Fluid Prostaglandins

Fertility and Sterility ·doi:10.1016/s0015-0282(16)45199-x

The association of endometriosis and infertility is well know. However, the exact mechanisms involved remain unclear. To study the effect of endometriosis on fertility, an experimental model was developed using New Zealand White rabbits. En…

article 1977

The use of an impeded androgen—danazol—in the management of benign breast disorders

·doi:10.1016/s0002-9378(16)33237-9

Danazol, an impeded androgen with moderate antigonadotropin properties, was administered to 58 patients with a variety of benign breast disorders. The disturbances were present from 3 months to 20 years; the ages ranged from 21 to 50 years.…