Quantitative Real Time PCR was used to analyze the mRNA expression levels of DCAMLK1. Representative qRT-PCR results (Ct values) for DCAMLK1 and control genes (ACTB and GAPDH) are shown. (DOCX 216 kb)
Quantitative Real Time PCR was used to analyze the mRNA expression levels of DCAMLK1. Representative qRT-PCR results (Ct values) for DCAMLK1 and control genes (ACTB and GAPDH) are shown. (DOCX 216 kb)
OBJECTIVE: Endometriosis is a benign gynaecological disease, affecting women during their reproductive years. Angiogenesis represents a crucial step in the pathogenesis of endometriosis, because endometriotic lesions require neovascularizat…
BACKGROUND: Current evidence suggests that endometrial-derived stem cells, spilled in the peritoneal cavity via retrograde menstruation, are key players in the establishment of endometriotic lesions. The aim of this study was to determine t…
BACKGROUND: Epithelial to mesenchymal transition (EMT) is a process in which epithelial cells lose polarity and cell-to-cell contacts and acquire the migratory and invasive abilities of mesenchymal cells. These abilities are thought to be p…
Trotz der hohen klinischen Relevanz der Endometriose war es bisher nicht möglich eine Spezialisierung im Rahmen eines zertifizierten Weiterbildungsprogrammes anzustreben/anzubieten.
OBJECTIVE: Gonadotropin releasing hormone agonists (GnRHa) decrease the expression of growth factors involved in the development of human endometriotic tissue. As endometriosis has been found to be associated with a mild increase in prolact…
Chorionic gonadotropin (CG) is indispensable for human pregnancy because it controls implantation, decidualization, and placental development. However, its particular role in the differentiation process of invasive trophoblasts has not been…
Neben den klassischen Methoden der Operation und der Bestrahlung zur Behandlung der Endometriose hat sich in den letzten 2 Jahrzehnten die medikamentös-hormonale Therapie sehr stark in den Vordergrund geschoben. Es scheint mir notwendig, di…