Naoki Terakawa

No ORCID on file · 77 papers in corpus · active 1986-2021

Study types

  • article 62
  • review 6
  • other 3
  • book-chapter 2
  • case-report 1

Condition tags

  • endometriosis 56
  • endometrioma 9
  • infertility 6
  • chronic_pelvic_pain 4
  • dysmenorrhea 3
  • dyspareunia 3
  • adenomyosis 1
article 2003
Gonadotropin-releasing hormone agonist treatment reduced production and circulating levels of interleukin-6 in patients with ovarian endometrioma
·doi:10.1016/s0015-0282(03)01501-2
article 2003
Gonadotropin-releasing hormone agonist treatment reduced serum interleukin-6 concentrations in patients with ovarian endometriomas
Fertility and Sterility ·doi:10.1016/s0015-0282(03)00609-5
case-report 2003
Ovarian endometrioid adenocarcinoma arising from endometriosis in a young woman
Gynecologic oncology ·doi:10.1016/j.ygyno.2003.08.005

BACKGROUND: The risk of ovarian cancer increases in women with a long history of ovarian endometriosis, particularly in postmenopausal women. We present here a case of malignant transformation of endometriosis occurring over a short time in…

article 2003
Tumor Necrosis Factor-α-Induced Interleukin-8 (IL-8) Expression in Endometriotic Stromal Cells, Probably through Nuclear Factor-κB Activation: Gonadotropin-Releasing Hormone Agonist Treatment Reduced IL-8 Expression
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2002-020666

Endometriosis, a common disease among women of reproductive age, is characterized by the presence of endometrial-like tissue outside the uterus. We previously reported that TNFalpha promoted proliferation of endometriotic stromal cells by i…

article 2002
Gonadotropine-releasing hormone agonist treatment reduced expression of interleukin-8 in stromal cells derived from ovarian endometrioma
·doi:10.1016/s0015-0282(02)04090-6
article 2002
Is Endometriosis Really Associated with Pain?
Gynecologic and obstetric investigation ·doi:10.1159/000066290

To address the contrasting findings regarding how pain is related to endometriosis, the relationship between pain and stage of endometriosis was dissected differently by the chief complaint to eliminate selection biases. A total of 1,092 wo…

article 2002
Laparoscopic Surgery for the Management of Ovarian Endometrioma
Gynecologic and obstetric investigation ·doi:10.1159/000066291

The purpose of this study was to evaluate the effects of laparoscopic surgery on the symptoms associated with ovarian endometrioma. We also examined serum IL-6 concentrations in patients with endometrioma. Ninety-two patients who underwent …

review 2002
Role of Cytokines in Endometriosis-Associated Infertility
Gynecologic and obstetric investigation ·doi:10.1159/000049420

Endometriosis, which is common in women of reproductive age, may affect fertility. It is also clear that mechanical disruption of the pelvic anatomy may cause infertility. However, our understanding of the association between the early stag…

article 2002
Tumor necrosis factor alpha promoted interleukin-8-induced proliferation of endometriotic stromal cells via nuclear factor-kB activation
·doi:10.1016/s0015-0282(02)03613-0
article 2001
[Epidemiology of endometriosis].
Nihon rinsho. Japanese journal of clinical medicine
review 2001
Role of cytokines in endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(01)01816-7
letter 2000
Adenomyosis in a patient with the Rokitansky-Kuster-Hauser syndrome
Fertility and Sterility ·doi:10.1016/s0015-0282(99)00643-3
editorial 2000
Altered gene expression and secretion of interleukin-6 in stromal cells derived from endometriotic tissues
Fertility and Sterility ·doi:10.1016/s0015-0282(99)00496-3
article 2000
Cytokine Levels in a Patient with Severe Ovarian Hyperstimulation Syndrome Before and After the Ultrafiltration and Reinfusion of Ascitic Fluid
·doi:10.1023/a:1009422218571
article 1999
Role of Cytokines in Progression of Endometriosis
Gynecologic and obstetric investigation ·doi:10.1159/000052857

Peritoneal fluid in women with endometriosis contains an increased number of activated macrophages that secrete a variety of cytokines, including interleukin (IL)-6, IL-8, vascular endothelial growth factor, and tumor necrosis factor-alpha …

article 1998
Pathogenetic Significance of Increased Levels of Interleukin-8 in the Peritoneal Fluid of Patients with Endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(98)00049-1
article 1997
Increased interleukin-6 levels in peritoneal fluid of infertile patients with active endometriosis
American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(97)70553-2
article 1995
Effect of gonadotropin-releasing hormone agonists, nafarelin, buserelin, and leuprolide, on experimentally induced endometriosis in the rat.
International journal of fertility and menopausal studies

OBJECTIVE -- The purpose of this study was to compare the potency of the gonadotropin-releasing hormone (GnRH) agonists nafarelin, buserelin, and leuprolide in a newly developed model of experimental endometriosis, thus further characterizi…

article 1993
No inhibitory effects of danazol estrogen production by ovaries of hypophysectomized rats stimulated by gonadotropins.

The effects of danazol on estrogen production by rat ovaries were investigated. Hypophysectomized immature female rats were injected daily with 2.5 or 5 IU of pregnant mare serum gonadotropin (PMS) and simultaneously daily given vehicle onl…

article 1992
Luteinized unruptured follicle in the early stages of endometriosis as a cause of unexplained infertility
American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(11)91673-1
article 1990
Effects of danazol, gonadotropin-releasing hormone agonist, and a combination of danazol and gonadotropin-releasing hormone agonist on experimental endometriosis
American Journal of Obstetrics and Gynecology ·doi:10.1016/0002-9378(90)90650-v
article 1989
[Studies on endocrine therapy of endometriosis].
Nihon Sanka Fujinka Gakkai zasshi

GnRH agonist and synthetic steroid such as Danazol, Medroxyprogesterone acetate (MPA) and Gestrinone are useful for the treatment of patients with endometriosis. These compounds induce atrophy and regression of endometriotic tissue, but the…

article 1989
Studies on GnRH Agonist Suppression of Estrogen Production in Patients with Endometriosis.
Endocrinologia japonica ·doi:10.1507/endocrj1954.36.611

The chronic administration of GnRH agonists to women results in the reversible suppression of estrogen production by the ovary. In the present study, the mechanism of the GnRH agonist suppression of estrogen production was investigated in p…

article 1988
Inhibitory effects of danazol and medroxyprogesterone acetate on [3H]thymidine incorporation in human endometrial cancer cells
·doi:10.1016/0022-4731(88)90216-6
article 1988
Preliminary report on the use of danazol in the treatment of endometrial adenomatous hyperplasia
·doi:10.1002/1097-0142(19881215)62:12<2618::aid-cncr2820621228>3.0.co;2-i

Since the authors recently reported that danazol inhibits the growth of human endometrial cancer cells in vitro, a clinical trial was initiated to examine whether danazol can regress adenomatous hyperplasia, a precursor of endometrial adeno…