Yang Wu

No ORCID on file · 8 papers in corpus · active 2015-2025

Study types

  • article 4
  • other 2
  • preprint 1
  • review 1

Condition tags

  • endometriosis 5
  • mesh:D004715 4
  • chronic_pelvic_pain 3
  • irritable_bowel_syndrome 2
  • dysmenorrhea 1
  • adenomyosis 1
  • dyspareunia 1
article 2025
Participation of COX2/mPGES1/PGE2 in mouse and human endometrial stromal decidualization
·doi:10.1186/s12917-025-04505-5

BACKGROUND: Prostaglandin E2 (PGE2) is vital for embryo implantation and decidualization. Whether COX2/mPGES1/PGE2 pathway is essential for mouse and human decidualization remains unclear. RESULTS: This study showed that mPGES1 was highly e…

article 2023
Evidence of shared genetic factors in the etiology of gastrointestinal disorders and endometriosis and clinical implications for disease management
Cell reports. Medicine ·doi:10.1016/j.xcrm.2023.101250

In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed. Using large-scale datasets, we report a genetic correlation between endometriosis and irritable bowel syndrome (IBS), peptic ulcer dise…

other 2023
Oxidatively generated DNA damage mediates the associations of exposure to phthalates with uterine fibroids and endometriosis: Findings from TREE cohort
Free radical biology & medicine ·doi:10.1016/j.freeradbiomed.2023.05.029

BACKGROUND: Epidemiological studies on phthalate exposures in associations with uterine fibroids (UF) and endometriosis (EMT) are inconsistent. The underlying mechanisms are poorly understood. OBJECTIVES: To investigate the relationships o…

preprint 2022
Evidence of shared genetic factors in the aetiology of gastrointestinal disorders and endometriosis and clinical implications for disease management
·doi:10.1101/2022.10.20.22281201

Abstract In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed; however, the factors driving this link remain largely unknown. Here, using large-scale multifaceted data including observation…

article 2021
Acupuncture for chronic pelvic pain in patients with SPID
·doi:10.1097/md.0000000000023916

BACKGROUND: Chronic pelvic pain (CPP) is one of the common sequela of pelvic inflammatory disease, the pathological factors are adhesions, scarring and pelvic congestion which caused by inflammation, often cause abdominal pain and lumbosacr…

article 2020
Adjuvant therapy of Chinese herbal medicine for the treatment of adenomyosis
Medicine ·doi:10.1097/md.0000000000020560

BACKGROUND: Adenomyosis is benign gynecologic condition with complex etiologies. Common symptoms associated with adenomyosis (AM) include menorrhagia, dysmenorrhea, chronic pelvic pain, metrorrhagia, and dyspareunia. Although Chinese herbal…

other 2019
Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases
Clinical epigenetics ·doi:10.1186/s13148-019-0648-7

BACKGROUND: Major challenges in understanding the functional consequences of genetic risk factors for human disease are which tissues and cell types are affected and the limited availability of suitable tissue. The aim of this study was to …

review 2015
Association between HSD17B1 rs605059 polymorphisms and the risk of uterine diseases: a systemic review and meta-analysis.
International journal of clinical and experimental pathology

The aim of this study was to evaluate the HSD17B1 gene polymorphisms in the risks of endometrial cancer, endometriosis and uterine leiomyoma by meta-analysis. A comprehensive electronic search was conducted in PubMed, Medline (Ovid), Embase…