Study types
- article 7
- preprint 2
- dissertation 1
Condition tags
- endometriosis 7
- chronic_pelvic_pain 2
- irritable_bowel_syndrome 2
- interstitial_cystitis 1
- endometrioma 1
- disambig:endometritis 1
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Tuberous sclerosis complex (TSC) is an autosomal dominant genetic and multi-spectrum disease, characterized by the development of benign hamartomas in multiple organ systems, which may be misdiagnosed as malignant neoplasms. We present the …
Background:Chronic endometritis is a persistent and localized inflammation of the endometrium. Clinically, antibiotics are used to treat CE, but there is a lack of optimal treatment protocols. Objectives:To evaluate the effectiveness and sa…
BACKGROUND Endometriosis affects approximately 10% of reproductive-age women and is frequently associated with chronic pelvic pain. Patients with endometriosis often experience comorbid depression and anxiety, but the underlying mechanisms …
) that were significantly associated with endometriosis risk through genetically regulated splicing events. Overall, this study detected transcript isoform-level and RNA splicing level specific changes, providing insights into the dynamic c…
In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed. Using large-scale datasets, we report a genetic correlation between endometriosis and irritable bowel syndrome (IBS), peptic ulcer dise…
Abstract In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed; however, the factors driving this link remain largely unknown. Here, using large-scale multifaceted data including observation…
Epidemiological studies have observed that risk of endometriosis is associated with history of cutaneous melanoma and vice versa. Evidence for shared biological mechanisms between the two traits is limited. The aim of this study was to inve…
AIMS: Notch1 signaling regulates microglia activation, which promotes neuroinflammation. Neuroinflammation plays an essential role in various kinds of pain sensation, including bladder-related pain in bladder pain syndrome/interstitial cyst…
STUDY QUESTION: Are genetic effects on endometrial gene expression tissue specific and/or associated with reproductive traits and diseases? SUMMARY ANSWER: Analyses of RNA-sequence data and individual genotype data from the endometrium iden…