Zi-Jiang Chen

No ORCID on file · 13 papers in corpus · active 1992-2025

Study types

  • article 7
  • other 5
  • review 1

Condition tags

  • adenomyosis 6
  • endometriosis 5
  • mesh:D004715 4
  • infertility 3
  • dysmenorrhea 2
  • chronic_pelvic_pain 1
other 2025
Journal of ovarian research ·doi:10.1186/s13048-025-01629-y

BACKGROUND: Infertility has become a world-wide public health problem. To identify women in a high-risk of infertility at an early stage when more treatments are available, early risk factors such as age at menarche (AAM) are being investig…

other 2023
Frontiers in medicine ·doi:10.3389/fmed.2023.1248274

OBJECTIVES: To elucidate the relationship between long-acting GnRH agonist (GnRHa) downregulation and assisted reproductive technology (ART) outcomes and identify the optimal duration of downregulation in patients with adenomyosis. DESIGN:…

other 2023
Mucosal immunology ·doi:10.1016/j.mucimm.2023.02.003

Immune dysregulation has long been proposed to be associated with adenomyosis, but the underlying mediators and mechanisms remain largely unexplored. Here, we used flow cytometry to investigate the alterations in immune cell subsets in aden…

article 2022
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2022.05.007

RESEARCH QUESTION: Adenomyosis is a common uterine disorder of uncertain causes. Can transcriptomic analyses of the endometrium and myometrium reveal potential mechanisms underlying adenomyosis pathogenesis? DESIGN: Transcriptomic profiles …

article 2020
Frontiers in genetics ·doi:10.3389/fgene.2020.00716

Adenomyosis is a prevalent, estrogen-dependent uterine disorder wherein endometrial cells are abnormally present in the myometrium and are surrounded by hyperplastic/hypertrophic smooth muscle. Its etiology is unclear, although endometrial …

other 2019
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2018.11.034

RESEARCH QUESTION: The prevalence of infertility in couples actively trying to conceive is 25%. What is the consultation-seeking behaviour, diagnosis and related treatment in infertile couples across China? DESIGN: Large cross-sectional po…

article 2019
Molecular human reproduction ·doi:10.1093/molehr/gaz040

Fibrotic tissue may contribute to the origin of some endometriosis-related symptoms, such as chronic pelvic pain and infertility. Alterations in the H19/miR-216a-5p/ACTA2 pathway may mediate the regulation of eutopic endometrial stromal cel…

article 2018
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-018-0375-5

BACKGROUND: Melatonin is a potential therapeutic agent for endometriosis, but its molecular mechanism is unclear. Here, we investigated the effect of melatonin on the epithelial-mesenchymal transition (EMT) in endometriotic endometrial epit…

article 2016

This study investigated the risk factors and early predictors for heterotopic pregnancy (HP) after in vitro fertilization and embryo transfer (IVF-ET). From January 2008 to January 2013, 41 cases of HP and 72 cases of intrauterine twin preg…

article 2013
Gynecologic and obstetric investigation ·doi:10.1159/000355101

AIMS: To study the effect of adenomyosis on in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes in infertile patients. METHODS: We performed a retrospective, database-searched cohort study based on 10,268 patients un…

review 2013
Molecular human reproduction ·doi:10.1093/molehr/gat040

Many genetic association studies have been performed to investigate disorders of female reproduction, such as polycystic ovary syndrome, premature ovarian failure and endometriosis. These disorders typically manifest heterogeneously, and th…

other 2011
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-9-9

BACKGROUND: To evaluate basal testosterone (T) levels during follicular phase of the menstrual cycle as a predictor for ovarian response and in vitro fertilization (IVF) outcome. METHOD: We analyzed data retrospectively from hospital-based…

article 1992
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1198779

In infertile women with adenomyosis, if a fresh embryo was planned for transfer, an ultra-long or long protocol might be beneficial. If antagonist and short protocols were used, whole embryos frozen followed by FET was recommended. In FET c…