Lin A

Cardiovascular disease (CVD) remains a significant cause of morbidity and mortality amongst women. While our general understanding of evaluation and treatment of CVD has greatly improved over the past decades, there is a gap in the knowledg…

Systems biology is primarily concerned with the dynamic study of biochemical metabolic processes in physical systems, the interplay of multiple signal transduction routes, gene regulatory networks, and disease causes, among other things. It…

We compare the success of sentinel lymph node (SLN) biopsy between standard laparoscopy and robotic-assisted laparoscopy (RAL) in patients with endometrial cancer. Patients with uterine epithelial tumour types undergoing staging surgery wer…

Ovarian cancer has a high mortality rate, primarily due to late diagnosis and complex pathogenesis. This study develops an integrative prognostic model combining genetic, clinical, and immunological data to predict outcomes in ovarian cance…

Natural killer (NK) cells, serving as pivotal mediators of innate immunity, play an important role in antitumor immunity. Immune checkpoint can be expressed on the surface of NK cells and meticulously regulates their activation states and e…

Background/Objectives: Intrauterine adhesion (IUA) is characterized by endometrial fibrocyte hyperplasia. The LIN28B gene is associated with many proliferative diseases. However, its association with IUA is entirely unknown. We hypothesized…

RESEARCH QUESTION: Does the NOD-like receptor protein 3 (NLRP3) inflammasome have an effect in adenomyosis? DESIGN: Fresh-frozen endometrial tissues and paraffin specimens were obtained from endometrial tissues from patients with adenomyos…

PurposeThis study aimed to evaluate the effectiveness of a random forest (RF) model in predicting clinical pregnancy outcomes from intrauterine insemination (IUI) and identifying significant factors affecting IUI pregnancy in a large Chines…

NADPH oxidase 4 (NOX4) plays an important role in the regulation of oxidative stress, which is associated with endometriosis. This study aims to investigate the effects of NOX4 in endometriosis and its molecular mechanisms. Clinical specime…

Endometriosis is a common disease of the female reproductive system and has malignant features. Although endometriosis by itself is a benign disease, its erosive growth characteristics lead to severe pelvic pain and female infertility. Unfo…

Surgical management for gynecologic malignancies often involves hysterectomy, often constituting the most common gynecologic surgery worldwide. Despite maximal surgical and medical care, gynecologic malignancies have a high rate of recurren…

To investigate the expression and clinical significance of nucleoside diphosphate kinase A (nm23-H1), p53, and integrin β1 in endometriosis, normal and ectopic endometrial tissues were collected and the levels of nm23-H1, p53, and integrin …

BackgroundHirschsprung disease (HSCR) is a rare congenital gastrointestinal disease characterized by the absence of intestinal submucosal and myometrial ganglion cells. Recently, researches indicated that miR-100 regulated the growth, diffe…

Endometriosis is characterized by eutopic endometrial cell 'metastasis' to ectopic foci. FOXA2 is a member of the forkhead transcription factor family, which may participate in transcriptional regulation in endometrial cells and contribute …