International journal of general medicine

Systems biology is primarily concerned with the dynamic study of biochemical metabolic processes in physical systems, the interplay of multiple signal transduction routes, gene regulatory networks, and disease causes, among other things. It…

BACKGROUND: The global burden of kidney stones is increasing, while di(2-ethylhexyl) phthalate (DEHP), a widespread plasticizer and endocrine-disrupting pollutant, has been implicated as a potential environmental risk factor. This study inv…

BACKGROUND: Infertility is a growing public health concern in developing nations, including Somalia, where medical, socioeconomic, and cultural factors profoundly affect reproductive health. This study aimed to determine the prevalence and …

PURPOSE: Acute pancreatitis is a common disease with limited supportive treatments. Finding effective biomarkers is of great significance for early diagnosis and therapy, as well as to achieve better prognosis. MATERIALS AND METHODS: The c…

AIM: To summarize current evidence on the molecular mechanisms by which the cervicovaginal microbiota mediates post-injury endometrial repair and to discuss relevant microbiota-targeted intervention strategies. METHODS: A narrative review …

OBJECTIVE: To explore the correlation between autoantibodies, ultrasonic endometrial receptivity parameters and early miscarriage in recurrent spontaneous abortion (RSA) patients during subsequent pregnancies, and to establish and validate …

BACKGROUND: Thin endometrium continues to pose a significant challenge in assisted reproductive technology (ART) cycles, necessitating further exploration of therapeutic approaches. Tamoxifen (TMXF) has been primarily used in ovarian stimul…

Oxidative stress, defined as an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, plays a critical role in female reproductive health, particularly in ovarian function. This review provides a comprehensive…

BACKGROUND: Immature teratoma is a malignant tumor and accounts for 1%-3% of ovary teratoma. The objective of this study was to find the potential single nucleotide polymorphisms (SNPs), copy number variations (CNVs) and drug targets in the…

OBJECTIVE: This study aimed to examine the effects and the efficacy of a combination of interventional embolization and endocrine hormone therapy for Pelvic congestion syndrome (PCS). METHODS: We retrospectively analyzed 132 patients diagn…

OBJECTIVE: To propose a prediction model aimed at increasing the live birth rate of patients undergoing two-cell embryo transfer while eliminating multiple pregnancy complications. METHODS: Women who underwent their first In Vitro Fertiliz…

OBJECTIVE: Refeeding syndrome (RFS) is a potentially life-threatening complication during nutritional rehabilitation in malnourished patients, especially those in intensive care units (ICUs). This study aimed to develop and internally valid…

OBJECTIVE: This study aims to investigate the association between the dynamics of routine metabolic markers and endometriosis severity. METHODS: A retrospective analysis was conducted on patients diagnosed with endometriosis at Zhongshan H…

Mifepristone is a well-established pharmaceutical agent in obstetrics and gynecology, which has expanded its therapeutic applications to Cushing's syndrome, meningioma, and even mental disease. The incidence of progesterone receptor modulat…

BACKGROUND: The achievement of a healthy live birth from a singleton pregnancy has become the primary objective of modern Assisted Reproductive Technology (ART). Consequently, the effective utilization of a single blastocyst is of paramount…

BACKGROUND: Female infertility is a distressing event to couples, and it is mainly caused by ovulatory disorders, pituitary gland dysfunction, fallopian tube blockage, and uterine abnormalities. This study aimed to determine the prevalence,…

OBJECTIVE: Infertility caused by endometriosis (EM) directly affects the possibility of pregnancy in women of gestational age. This study aims to establish a prediction model to accurately predict the natural pregnancy outcome of patients w…

PURPOSE: To explore the early diagnostic value of superb microvascular imaging (SMI) features within the rotator cuff gap for frozen shoulder. PATIENTS AND METHODS: This prospective study enrolled patients with acute early-stage frozen sho…

OBJECTIVE: To explore the active substances and targets of Danbie Capsules in Endometriosis therapy. METHODS: This study was conducted through TCMSP and published literature screened and obtained 183 active substances of Danbie Capsules, c…

OBJECTIVE: To evaluate if a brief educational intervention for primary health care staff regarding endometriosis gives sustainable knowledge of endometriosis symptoms and if a brief questionnaire for women seeking care for common symptoms i…

BACKGROUND AND AIMS: Increasing interest in hypnotherapy's application for a wide range of health conditions has spurred a rise in global research and publications. This study aims to visualize development patterns and current research hots…

BACKGROUND: Ovarian cysts are common diseases among women. They might affect reproductive function in severe cases, and thus, patients with ovarian cysts often have negative emotions. PURPOSE: In this study, we elucidated the risk factors …

OBJECTIVE: This study aims to explore formula patterns and application rules for SP6 as the main acupoint in prescriptions, utilizing association rules. METHODS: We conducted an extensive search in databases including China National Knowle…

BACKGROUND: Endometriosis, a common gynecological condition, can cause symptoms such as dysmenorrhea, infertility, and abnormal bleeding, which can negatively affect a woman's quality of life. In the current study, the pathophysiological me…

BACKGROUND: To investigate the existence and degree of correlation between benign ovarian tumors and physiological indicators such as reproductive hormones and tumor markers. METHODS: A total of 150 patients with benign ovarian tumors admi…