Wise LA

BackgroundFemale sexual function is important for sexual well-being, general health, fertility, and relationship satisfaction. Distressing impairments in sexual function, clinically recognized as female sexual dysfunction (FSD), can manifes…

BackgroundFemale sexual function is important for positive sexual expression, relationship satisfaction, and overall health and wellbeing. Female sexual dysfunction (FSD), which affects ∼40% of premenopausal women, may manifest as issues wi…

OBJECTIVE: To assess whether exposure to lower-chlorinated PCBs from building materials is associated with increased incidence of UL, endometriosis, and PCOS in female residents. METHODS: We studied 21,619 residents of two Danish partially…

BackgroundFertility success among mixed-sex couples often depends on frequency and timing of sexual intercourse, yet little research has evaluated the association between preconception sexual function and time-to-pregnancy.ObjectiveTo evalu…

The health of prospective parents before conception (i.e., preconception health) has important intergenerational consequences. Although oral health is associated with several reproductive outcomes, it is often absent from preconception heal…

INTRODUCTION: Menstrual health is a key patient-reported outcome beyond its importance as a general indicator of health and fertility. However, menstrual function was not measured in the clinical trials of COVID-19 vaccines. The purpose of …

ObjectiveTo use self-reported preconception data to derive models that predict the risk of miscarriage.DesignProspective preconception cohort study.SettingNot applicable.PatientsStudy participants were female, aged 21-45 years, residents of…

BackgroundBlack women and people with uteri have utilized collectivistic and relational practices to improve health outcomes in the face of medical racism and discrimination for decades. However, there remains a need for interventions to im…

Objective: To compare 12-month post-treatment health-related quality of life (HR-QoL) and symptom severity (SS) changes among patients with symptomatic uterine fibroids (SUF) not seeking fertility and undergo a hysterectomy, abdominal myome…

Research questionAre gravidity, parity and breastfeeding history associated with anti-Müllerian hormone concentration among African-American women of reproductive age?DesignThis study included baseline data from the Study of the Environment…

BackgroundMetals may influence reproductive health, but few studies have investigated correlates of metal body burden among reproductive-aged women outside of pregnancy. Furthermore, while there is evidence of racial disparities in exposure…

ObjectivesTo evaluate the association between preconception contraceptive use and miscarriage.DesignProspective cohort study.SettingResidents of the United States of America or Canada, recruited from 2013 until the end of 2022.Participants1…

ObjectiveTo evaluate the association between seasonal influenza vaccination and miscarriage using data from an ongoing, prospective cohort study.MethodsWe analyzed 2013-2022 data from PRESTO (Pregnancy Study Online), a prospective prepregna…

BackgroundDespite the high prevalence of female sexual dysfunction in population-based studies and the importance of sexual functioning for mixed-sex couples attempting conception, little is known about female sexual function in the preconc…

Background: Quality of life (QOL) and psychological health has been reported to be decreased among women with gynecological conditions such as uterine fibroids (UFs). Materials and Methods: Women enrolled in the Comparing Options for Manage…

PurposeTo evaluate the relationships among history of asthma, asthma severity, and spontaneous abortion (SAB).MethodsPregnancy Study Online is a preconception cohort study of North American couples. During the preconception period, female p…

BackgroundInfertility affects up to 15% of couples. In vitro fertilization (IVF) treatment has modest success rates and some factors associated with infertility and poor treatment outcomes are not modifiable. Several studies have assessed t…

Study questionCan we derive adequate models to predict the probability of conception among couples actively trying to conceive?Summary answerLeveraging data collected from female participants in a North American preconception cohort study, …

BackgroundRefusal to participate in studies related to sexual health can compromise the internal and external validity of findings. Research examining non-response to sexual health studies has primarily focused on predictors such as specifi…

BackgroundMigraine is common among females of reproductive age (estimated prevalence:17-24%) and may be associated with reproductive health through underlying central nervous system excitability, autoimmune conditions, and autonomic dysfunc…

PurposeTo prospectively examine the association between time-to-pregnancy (TTP) and postpartum depression (PPD) and determine whether perceived stress during early pregnancy mediated this association.MethodsIn Pregnancy Study Online, an int…

Study questionTo what extent is female preconception antibiotic use associated with fecundability?Summary answerPreconception antibiotic use overall was not appreciably associated with fecundability.What is known alreadyAntibiotics are comm…

BackgroundPhthalates are endocrine-disrupting chemicals that are widely present in consumer products. In the United States, Black women are more highly exposed to phthalates than other racial/ethnic groups, yet information on predictors of …

Study questionDo daughters of older mothers have lower fecundability?Summary answerIn this cohort study of North American pregnancy planners, there was virtually no association between maternal age ≥35 years and daughters' fecundability.Wha…