PurposeTo evaluate the relationships among history of asthma, asthma severity, and spontaneous abortion (SAB).MethodsPregnancy Study Online is a preconception cohort study of North American couples. During the preconception period, female p…
BACKGROUND: Associations between benign gynecologic pathologies and circulating inflammatory markers are unknown. Our goal was to evaluate self-reported history of benign gynecologic pathology and subsequent alterations in systemic inflamma…
PURPOSE: Endometriosis is a chronic inflammatory disease affecting the reproductive, gastrointestinal, and urinary systems. We examined changes in labor force participation amongst women with endometriosis following diagnosis. METHODS: We …
PurposeTo prospectively examine the association between time-to-pregnancy (TTP) and postpartum depression (PPD) and determine whether perceived stress during early pregnancy mediated this association.MethodsIn Pregnancy Study Online, an int…
PurposeThe aim of this study was to evaluate the association between menstrual cycle characteristics in early life and adulthood and fecundability.MethodsPregnancy Study Online (PRESTO) is an Internet-based preconception cohort study of pre…
PurposePoor and disparate reproductive health outcomes in the United States may be related to inadequate and differential receipt of women's health care. We investigated trends in and determinants of adult U.S. women's health service use, 2…
Assessment of cortisol concentrations in hair is one of the latest innovations for measuring long-term cortisol exposure. We performed a systematic review of correlates of cortisol in human hair to inform the design, analysis, and interpret…
PurposeAge at menopause, a major marker in the reproductive life, may bias results for evaluation of breast cancer risk after menopause.MethodsWe followed 38,948 premenopausal women in 1980 and identified 2,586 who reported hysterectomy wit…
PurposePhysical activity may influence ovarian cancer risk and outcomes through effects on ovulation, inflammatory markers, and other processes. We examined associations between self-reported physical activity and ovarian cancer risk and su…
PurposeThis study investigated whether the association between passive smoking exposure and primary dysmenorrhea is modified by two susceptibility genes, cytochrome P450 1A1 (CYP1A1)MspI and CYP1A1HincII.MethodsWe recruited 1645 female text…
PurposeWe examined the association between endometriosis and exposure to polybrominated biphenyls (PBBs) and polychlorinated biphenyls (PCBs) among women inadvertently exposed to PBBs in 1973.MethodsSerum PBBs and PCBs were measured in the …
PurposePrimary biliary cirrhosis is an autoimmune disease with female predominance that leads to liver failure. The goal of this study was to identify reproductive risk factors associated with this disease.MethodsWe compared 182 cases of PB…
PurposeRisk factors for endometriosis were identified through data obtained from a case-control study at Brigham and Women's Hospital in Boston, Massachusetts.MethodsCases were 50 women with infertility-associated endometriosis. The primary…
This study reports the descriptive epidemiology of hysterectomy in the Province of Quebec, Canada, from 1981 to 1988. Data on hysterectomies (n = 150,849) among women 15 years and older were obtained from MED-ECHO, a computerized database o…