Michael Reed

No ORCID on file · 5 papers in corpus · active 1992-2008

Study types

  • article 4
  • review 1

Condition tags

  • endometriosis 2
  • infertility 1
article 2008
Inhibition of Steroid Sulfatase Activity in Endometriotic Implants by STX64 (667Coumate): A Potential New Therapy
TheScientificWorldJournal ·doi:10.1100/tsw.2008.164

Endometriosis is a common and debilitating condition of women in their reproductive age that is associated with pain and infertility. Current medical treatments are only partially effective and associated with wide-ranging side effects. New…

article 2007
Inhibition of steroid sulphatase activity in endometriotic implants by 667 COUMATE: a potential new therapy
Human Reproduction ·doi:10.1093/humrep/dem308

BACKGROUND: Local biosynthesis of estrogens is thought to be important for the maintenance and growth of endometriotic implants. In addition to the formation of estrogen via the aromatase pathway, steroid sulphatase (STS), which is responsi…

review 1992
Inhibition of oestrogen synthesis in postmenopausal women with breast cancer
·doi:10.1016/0960-0760(92)90200-3
article 1992
Oestrogen sulphatase activity in hormone‐dependent and hormone‐independent breast‐cancer cells: Modulation by steroidal and non‐steroidal therapeutic agents
·doi:10.1002/ijc.2910500614

Oestrogen sulphatase may play an important role in providing intracellular oestrogens from E1S for the growth and maintenance of breast tumours. In this study, we characterized oestrogen sulphatase in the hormone-dependent (ER/PR+) MCF-7 an…

article 1992
The Origin of Oestrone Sulphate in Normal and Malignant Breast Tissues in Postmenopausal Women
·doi:10.1055/s-2007-1003382

Conversion of oestrone sulphate to oestrone has been suggested to make a major contribution to the level of oestrone found in breast tissues. In order to examine the ability of breast tissues to take up oestrone sulphate (E1S), 3H E1S or E1…