Jun Shao

No ORCID on file · 15 papers in corpus · active 2013-2023

Study types

  • article 10
  • review 4
  • other 1

Condition tags

  • endometriosis 14
  • mesh:D004715 12
  • adenomyosis 1
article 2023
Bioscience trends ·doi:10.5582/bst.2022.01501

Endometriosis is a chronic inflammatory disease. The immune-checkpoint molecules CD226 and TIGIT play an important role in regulating T cells' function. However, little is known about the proportion and function of CD226 and TIGIT on CD4+ T…

review 2022
International journal of medical sciences ·doi:10.7150/ijms.71972

Interleukin-17 (IL-17) is known as a Th17-cell-derived proinflammatory cytokine, which plays a pivotal role in several inflammatory and autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis, and psoriasis. Eme…

review 2020
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13266

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid-origin cells which have immunosuppressive activities in several conditions, such as cancer and inflammation. Recent research has also associated MDSCs with numero…

review 2019
Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-019-03056-x
other 2019
International journal of molecular medicine ·doi:10.3892/ijmm.2018.4021

Angiogenesis is an essential process involved in various physiological, including placentation, and pathological, including cancer and endometriosis, processes. Melatonin (MLT), a well‑known natural hormone secreted primarily in the pineal …

article 2018
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13067

PROBLEM: Endometriosis (EM) is a chronic immunoinflammatory disease associated with an abnormal immunotolerant microenvironment. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that play a m…

review 2018
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12839

Melatonin is a neurohormone synthesized from the aromatic amino acid tryptophan mainly by the pineal gland of mammals. Melatonin acts as a broad-spectrum antioxidant, powerful free radical scavenger, anti-inflammatory agent, anticarcinogeni…

article 2017
Cell death & disease ·doi:10.1038/cddis.2017.95

Abstract Endometriosis is an estrogen-dependent inflammatory disease. The anti-inflammatory cytokine IL-10 is also increased in endometriosis. IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses. …

article 2016
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0089

Endometriosis (EMS) is associated with an abnormal immune response to endometrial cells, which can facilitate the implantation and proliferation of ectopic endometrial tissues. It has been reported that human endometrial stromal cells (ESCs…

article 2016
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0278

Macrophages play an important role in the origin and development of endometriosis. Estrogen promoted the growth of decidual stromal cells (DSCs) by downregulating the level of interleukin (IL)-24. The aim of this study was to clarify the ro…

article 2014
International journal of clinical and experimental pathology

It has reported that interleukin-22 (IL-22) promotes the invasion of tumor cells. IL-22 in the endometriotic milieu stimulates the proliferation of human endometrial stromal cells (ESCs). The present study aimed to elucidate whether and how…

article 2014
International journal of clinical and experimental pathology

It has reported that human endometrial stromal cells (ESCs) express thymic stromal lymphopoietin (TSLP), and TSLP concentrations in the serum and peritoneal fluid were higher in women with endometriosis. Endometriosis is an estrogen-depende…

article 2013
International journal of clinical and experimental pathology

Interleukin-22 (IL-22) is a member of the IL-10 cytokine family and plays critical roles in inflammation, immune surveillance, and tissue homeostasis. However, whether IL-22 regulates the growth of endometrial stromal cells (ESCs), and part…

article 2013
International journal of clinical and experimental pathology

Nonmetastatic gene 23-H1 (NME1, also known as nm23-H1) is a wide-spectrum tumor metastasis suppressor gene that plays an important role in suppressing the proliferation, adhesion and invasion of endometrial stromal cells (ESCs). The present…

article 2013
Human Reproduction ·doi:10.1093/humrep/det248

STUDY QUESTION: Is Nometastatic gene 23-H1 (NME1, also known as nm23-H1) involved in regulating the biological behavior of endometrial stromal cells (ESCs), and does it participate in the pathogenesis of endometriosis? SUMMARY ANSWER: NME1 …