Lonard DM

No ORCID on file · 6 papers in corpus · active 2014-2022

Study types

  • article 1

Condition tags

  • endometriosis 1
2022
Frontiers in reproductive health ·doi:10.3389/frph.2022.1033581

Steroid receptor coactivator-3 (SRC-3; also known as NCOA3 or AIB1) is a member of the multifunctional p160/SRC family of coactivators, which also includes SRC-1 and SRC-2. Clinical and cell-based studies as well as investigations on mice h…

article 2022
Reproduction (Cambridge, England) ·doi:10.1530/rep-22-0123

Although a non-malignant gynecological disorder, endometriosis displays some pathogenic features of malignancy, such as cell proliferation, migration, invasion and adaptation to hypoxia. Current treatments of endometriosis include pharmacot…

2022
iScience ·doi:10.1016/j.isci.2022.105321

We report the quaternary structure of core transcriptional complex for the full-length human progesterone receptor-B (PR-B) homodimer with primary coactivator steroid receptor coactivator-2 (SRC-2) and the secondary coactivator p300/CREB-bi…

2021
The Journal of endocrinology ·doi:10.1530/joe-20-0511

Tissue parenchyma is the functional unit of an organ and all of the remaining cells within that organ collectively make up the tissue stroma. The stroma includes fibroblasts, endothelial cells, immune cells, and nerves. Interactions between…

2018
Biology of reproduction ·doi:10.1093/biolre/ioy060

Speckle-type poz protein (SPOP) is an E3-ubiquitin ligase adaptor for turnover of a diverse number of proteins involved in key cellular processes such as chromatin remodeling, transcriptional regulation, and cell signaling. Genomic analysis…

2014
Annual review of medicine ·doi:10.1146/annurev-med-051812-145316

Transcriptional coregulators (coactivators and corepressors) have emerged as the principal modulators of the functions of nuclear receptors and other transcription factors. During the decade since the discovery of steroid receptor coactivat…