Khorram O

No ORCID on file · 9 papers in corpus · active 1993-2019

Study types

  • article 3
  • other 2

Condition tags

  • endometriosis 4
  • infertility 1
2019
Cross-talk between miR-29c and transforming growth factor-β3 is mediated by an epigenetic mechanism in leiomyoma.
Fertility and sterility ·doi:10.1016/j.fertnstert.2019.07.1324

ObjectiveTo determine the expression of miR-29c and its target gene transforming growth factor-β3 (TGF-β3) in leiomyoma and the mechanisms of their reciprocal regulation.DesignExperimental study.SettingAcademic research laboratory.Patient(s…

2014
miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis.
PloS one ·doi:10.1371/journal.pone.0095370

We have previously reported that leiomyoma expressed lower levels of miR-200c and elevated IL8 as compared to paired myometrium. Here we addressed the regulatory functions of miR-200c on the expression of inflammatory mediators and cellular…

2012
Altered endometrial expression of endothelial nitric oxide synthase in women with unexplained recurrent miscarriage and infertility.
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2012.07.004

Endothelial nitric oxide synthase (eNOS) has diverse roles in the female reproductive system including a role in blastocyst implantation. Aberrant expression of eNOS could therefore be significant in the pathogenesis of disorders of implant…

2009
Influence of progesterone on endometrial nitric oxide synthase expression.
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.05.019

ObjectiveTo determine the effect of P on nitric oxide synthase (NOS) expression in human endometrial epithelial cells.DesignLaboratory-based study.SettingUniversity-based research institute.Patient(s)None.Intervention(s)The effect of P on t…

article 2002
Alterations in expression of endometrial endothelial nitric oxide synthase and αvβ3 integrin in women with endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(02)03347-2

ObjectiveTo determine the expression of endometrial endothelial nitric oxide synthase (eNOS) protein and alpha(v)beta(3) integrin in patients with and without endometriosis.DesignCase-control cohort study.SettingUniversity-based tertiary ca…

other 2002
Uterine and ovarian aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear translocator (ARNT) mRNA expression in benign and malignant gynaecological conditions
Molecular human reproduction ·doi:10.1093/molehr/8.1.75

The transcriptional regulators aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear translocator (ARNT) modulate the transcription of genes involved in cellular differentiation and proliferation. In this study, we investiga…

article 2001
Human uterine and ovarian expression of growth hormone–releasing hormone messenger RNA in benign and malignant gynecologic conditions
Fertility and Sterility ·doi:10.1016/s0015-0282(00)01658-7

ObjectiveTo determine uterine and ovarian expression of growth hormone-releasing hormone (GHRH) messenger RNA (mRNA) in benign and pathologic gynecologic states.DesignCase-control study.SettingTertiary-care academic department.Patient(s)Wom…

other 1995
Interleukin-8 concentrations are elevated in peritoneal fluid of women with endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)57506-2

OBJECTIVE: To investigate the presence of interleukin-8 (IL-8), a macrophage-derived angiogenic factor, in peritoneal fluid (PF) of women with and without endometriosis. DESIGN: Case-control study. SETTING: University hospital. PATIENTS:…

article 1993
Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis
American Journal of Obstetrics and Gynecology ·doi:10.1016/0002-9378(93)90433-j

ObjectiveEndometriosis is a common gynecologic disorder in which the concentration and activation of peritoneal macrophages are increased. The goal of this study was to quantify pelvic fluid concentrations of two cytokines involved in macro…