M D Menger

No ORCID on file · 9 papers in corpus · active 2005-2021

Study types

  • article 6
  • review 2
  • other 1

Condition tags

  • mesh:D004715 9
  • endometriosis 9
article 2021
Differences in growth and vascularization of ectopic menstrual and non-menstrual endometrial tissue in mouse models of endometriosis
Human Reproduction ·doi:10.1093/humrep/deab139

STUDY QUESTION: Is there a difference in the growth and vascularization between murine endometriotic lesions originating from menstrual or non-menstrual endometrial fragments? SUMMARY ANSWER: Endometriotic lesions developing from menstrual …

article 2014
Combined blockade of angiotensin II type 1 receptor and activation of peroxisome proliferator-activated receptor-  by telmisartan effectively inhibits vascularization and growth of murine endometriosis-like lesions
Human Reproduction ·doi:10.1093/humrep/deu035

STUDY QUESTION: Is telmisartan effective in the treatment of endometriosis? SUMMARY ANSWER: Combined blockade of angiotensin II type 1 receptor (AT1R) and activation of peroxisome proliferator-activated receptor (PPAR)-γ by telmisartan inhi…

article 2013
Resveratrol is a potent inhibitor of vascularization and cell proliferation in experimental endometriosis
Human Reproduction ·doi:10.1093/humrep/det031

STUDY QUESTION: Does the phytochemical compound resveratrol inhibit vascularization of endometriotic lesions? SUMMARY ANSWER: Resveratrol suppresses the development of new microvessels in endometriotic lesions by inhibiting endothelial cell…

review 2012
Anti-angiogenic treatment strategies for the therapy of endometriosis
Human reproduction update ·doi:10.1093/humupd/dms026

BACKGROUND Angiogenesis, i.e. the development of new blood vessels from pre-existing ones, represents an integral part in the pathogenesis of endometriosis. During the last decade, an increasing number of studies have therefore focused on t…

other 2012
Xanthohumol inhibits growth and vascularization of developing endometriotic lesions
Human Reproduction ·doi:10.1093/humrep/des095

BACKGROUND: Xanthohumol is a prenylated flavonoid isolated from hops, which is known to act as a pleiotropic cancer chemopreventive agent owing to its anti-proliferative, anti-inflammatory and anti-angiogenic properties. In the present stud…

article 2011
In vitro and in vivo evaluation of the anti‐angiogenic actions of 4‐hydroxybenzyl alcohol
British journal of pharmacology ·doi:10.1111/j.1476-5381.2011.01292.x

BACKGROUND AND PURPOSE: 4-Hydroxybenzyl alcohol (HBA) is a phenolic plant compound, which has been shown to influence many cellular mechanisms. In the present study, we analysed in vitro and in vivo the anti-angiogenic actions of this pleio…

review 2011
Vasculogenesis: a new piece of the endometriosis puzzle
Human reproduction update ·doi:10.1093/humupd/dmr023

BACKGROUND; Endometriosis is a complex disease with a multifactorial pathogenesis, which is crucially dependent on the development of new blood vessels. Based on the current literature, the present review highlights the fact that the neovas…

article 2006
Rapamycin induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation
British journal of pharmacology ·doi:10.1038/sj.bjp.0706857

BACKGROUND AND PURPOSE: Rapamycin is a widely used drug with antifungal, immunosuppressant and antiangiogenic effects. Herein, we studied whether immunosuppressive doses of rapamycin are capable of influencing endometriotic lesions. EXPERIM…

article 2005
Combined inhibition of vascular endothelial growth factor (VEGF), fibroblast growth factor and platelet-derived growth factor, but not inhibition of VEGF alone, effectively suppresses angiogenesis and vessel maturation in endometriotic lesions
Human Reproduction ·doi:10.1093/humrep/dei308

BACKGROUND: Angiogenesis represents the crucial step in the pathogenesis of endometriosis, because endometriotic lesions require neovascularization to establish, proliferate and invade inside the peritoneal cavity. To elucidate the role of …