Fabio Barra

Background and Objectives: Endometriosis is a chronic, estrogen-dependent inflammatory disease with multifactorial pathogenesis. Increasing evidence suggests that alterations in the gut and reproductive tract microbiota may contribute to di…

Objective To systematically assess the prevalence, ultrasonographic characteristics, and clinical correlates of findings suggestive of deep endometriosis (DE) in postmenopausal women undergoing routine gynecological evaluation. Methods This…

Objective To systematically assess the prevalence, ultrasonographic characteristics, and clinical correlates of findings suggestive of deep endometriosis (DE) in postmenopausal women undergoing routine gynecological evaluation. Methods This…

INTRODUCTION: Hormonal therapy is the cornerstone of long-term endometriosis management, especially for women deferring surgery. In patients with comorbid migraine - a common, disabling condition - therapeutic choices must balance efficacy …

Endometriosis is a chronic gynecologic disease that needs newer and safer treatments. The proposed work aims to develop a nanosystem based on gold nanoparticles (AuNPs) to actively target human endometriosis CD44(+) cells and significantly …

INTRODUCTION: Medical therapy is crucial in the long-term management of endometriosis, and its clinical efficacy must be balanced with a favorable safety profile. AREAS COVERED: This review aims to provide a comprehensive overview of availa…

INTRODUCTION: Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting up to 10% of reproductive-aged women. Current therapies are predominantly hormone-based and offer symptomatic relief without correcting the immune d…

BACKGROUND: Bowel endometriosis is one of the more severe manifestations of deep endometriosis; it may cause pain and intestinal symptoms. The noninvasive diagnosis of bowel endometriosis is of crucial importance in planning the management …

Deep endometriosis (DE) frequently affects pelvic organs and may impair urinary function through both direct involvement and surgical nerve disruption. Minimally invasive excision is the standard treatment for symptomatic DE, but its impact…

OBJECTIVE: The objective of the current study was to evaluate the "twisting sign," defined as uterine fundus rotation observed on transvaginal sonography (TVS), as a potential soft marker for deep endometriosis (DE) and its association with…

Background/Objectives Bowel endometriosis (BE) is defined as the presence of endometrial-like tissue in the muscular layer of the bowel wall. When BE does not cause severe obstruction to fecal transit, not leading to (sub)occlusive symptoms…

Background/Objectives: Bowel endometriosis (BE) is characterized by the presence of endometrial-like tissue within the muscular layer of the bowel wall. When BE does not result in the severe obstruction to fecal transit and in the absence o…

Ovarian endometriomas (OEs) are commonly detected by ultrasound in individuals affected by endometriosis. Although surgery was widely regarded in the past as the gold standard for treating OEs, especially in the case of large cysts, the sur…

Deep endometriosis (DE) can be localized in the parametrium, a complex bilateral anatomical structure, sometimes necessitating intricate surgical intervention due to the potential involvement of autonomic nerves, uterine artery, and ureter.…

This narrative review aims to summarize available evidence on the IVF-associated outcomes after surgery for endometriosis. Only one retrospective study investigated if surgical treatment of superficial/peritoneal endometriosis may modify th…

INTRODUCTION: Endometriosis and pelvic inflammatory disease (PID) are gynecological conditions affecting women of reproductive age and causing pain symptoms. The symptoms caused by these conditions are similar; thus, the differential diagno…

ObjectiveTo study the ultrasonographic diagnostic accuracy and characteristics of parametrial endometriosis comprehensively.DesignThis prospective study enrolled patients with suspected deep endometriosis (DE) scheduled for laparoscopic sur…

INTRODUCTION: Endometriosis is an estrogen-dependent disease that gives rise to pelvic pain and infertility. Although estroprogestins and progestins currently stand as the first-line treatments for this condition, demonstrating efficacy in …