Akahane T

No ORCID on file · 5 papers in corpus · active 2005-2020

Study types

  • article 2
  • other 1

Condition tags

  • endometriosis 3
2020
Scientific reports ·doi:10.1038/s41598-020-69488-9

The use of primary patient-derived organoids for drug sensitivity and resistance testing could play an important role in precision cancer medicine. We developed expandable ovarian cancer organoids in < 3 weeks; these organoids captured the …

2013
Japanese journal of clinical oncology ·doi:10.1093/jjco/hyt125

ObjectivePrevious studies have reported an association between endometrial cancer and the risk of metabolic syndrome; however, the pattern of endometrial cancer-associated dyslipidemia is not well understood. The standard therapy for endome…

article 2010
Nature genetics ·doi:10.1038/ng.612

Although the pathogenesis of endometriosis is not well understood, genetic factors have been considered to have critical roles in its etiology. Through a genome-wide association study and a replication study using a total of 1,907 Japanese …

article 2007
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0b013e31802b41a8

To probe the mechanism of the development of ovarian cancer from endometriosis, which is a multistep process that involves the activation of oncogenes and inactivation of tumor suppressor genes, we evaluated p53 mutations in solitary endome…

other 2005
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/01.pgp.0000165173.90339.a2

Ovarian clear-cell carcinoma (OCCA) and ovarian endometrioid carcinoma (OEMC) are often associated with endometriosis. This study determined the immunohistochemical expression of steroid hormone receptors and cancer-related genes in OCCA an…