James Segars

No ORCID on file · 19 papers in corpus · active 2004-2026

Study types

  • article 9
  • review 6
  • other 4

Condition tags

  • endometriosis 19
  • mesh:D004715 15
  • adenomyosis 4
  • chronic_pelvic_pain 4
  • infertility 3
  • mesh:D017699 3
  • die_deep_infiltrating 1
  • dysmenorrhea 1
review 2026
Journal of gynecology obstetrics and human reproduction ·doi:10.1016/j.jogoh.2026.103170

OBJECTIVE: Up to 1.6% of patients with endometriosis develop epithelial ovarian carcinoma. The genetic overlap between endometriosis and ovarian cancer has not been fully characterized. This review aims to describe the current literature on…

other 2026
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2026.02.042

STUDY OBJECTIVE: To develop and validate a non-invasive, blood-based diagnostic assay for endometriosis that performs accurately across menstrual cycle phases and complements existing imaging modalities. DESIGN: Multicenter case-control st…

other 2025
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-01940-5

A systematic review was conducted pertaining to the biologic processes of cumulus cells and measures of oocyte quality. The initial search yielded 18,549 articles, and after screening, 65 studies were included in this review. Extracted data…

review 2024
F&S reviews ·doi:10.1016/j.xfnr.2024.01.003
review 2024
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-024-01515-w
review 2023
Nutrients ·doi:10.3390/nu15061439

Green tea is harvested from the tea plant Camellia sinensis and is one of the most widely consumed beverages worldwide. It is richer in antioxidants than other forms of tea and has a uniquely high content of polyphenolic compounds known as …

article 2021
The Journal of Pathology ·doi:10.1002/path.5778

Adenomyosis and peritoneal endometriosis are common gynecologic lesions; they are characterized by aberrant locations of normal-appearing endometrium in myometrium and peritoneal surface, respectively. Both ectopic lesions are speculated to…

article 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00127-z
article 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00201-x
review 2020
Seminars in reproductive medicine ·doi:10.1055/s-0040-1718922

Adenomyosis represents a unique pathophysiological condition in which normal-appearing endometrial mucosa resides within myometrium and is thus protected from menstrual shedding. The resulting ectopic presence of endometrial tissue composed…

review 2020
Endocrine reviews ·doi:10.1210/endrev/bnaa012

Selective progesterone receptor modulators (SPRMs) are a new class of compounds developed to target the progesterone receptor (PR) with a mix of agonist and antagonist properties. These compounds have been introduced for the treatment of se…

article 2018
Contemporary clinical trials ·doi:10.1016/j.cct.2018.03.002
article 2017
The New England journal of medicine ·doi:10.1056/nejmoa1614814

BACKGROUND: Endometriosis, defined as the presence of ectopic endometrial stroma and epithelium, affects approximately 10% of reproductive-age women and can cause pelvic pain and infertility. Endometriotic lesions are considered to be benig…

article 2011
Obstetrics and gynecology ·doi:10.1097/aog.0b013e318223fed0

OBJECTIVE: To study whether pain location is related to lesion location in women with chronic pelvic pain and biopsy-proven endometriosis. METHODS: A secondary analysis was performed to compare self-reported pain location with recorded lapa…

article 2008
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.11.038
article 2008
Obstetrics and gynecology ·doi:10.1097/01.aog.0000297307.35024.b5

OBJECTIVE: To evaluate whether 6 months of raloxifene was effective in treatment of chronic pelvic pain in women with endometriosis. METHODS: Women with chronic pelvic pain and no endometriosis treatment for 6 months underwent laparoscopy f…

other 2008
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.05.042

OBJECTIVE: To correlate histology with endometriosis characteristics. DESIGN: Secondary data analysis. SETTING: Government research hospital. PATIENT(S): One hundred thirty-three women with chronic pelvic pain and endometriosis who under…

other 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.06.053

OBJECTIVE: To evaluate the expression of estrogen receptor alpha (ERalpha), estrogen receptor beta (ERbeta), and breast cancer nuclear receptor auxiliary factor (Brx) in eutopic endometrium of normal women and women with endometriosis. DES…

article 2004
Fertility and Sterility ·doi:10.1016/j.fertnstert.2003.11.059