Wang X

BackgroundClinical pharmacology teaching is often limited by abstract content and insufficient integration of anatomical structure, physiological regulation, and drug targets. Traditional teaching models make it difficult for interns to tra…

Levonorgestrel-releasing intrauterine system (LNG-IUS) expulsion rates are markedly elevated (15-37.5%) in patients with adenomyosis compared to those with normal uteri (3-10%), significantly compromising treatment efficacy and adherence. E…

Jin Zhao,* Jianliang Chen,* Xiaoe Wang,* Huabin Wang* Department of Obstetrics and Gynecology, the First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang,…

BackgroundOvarian cancer is a lethal gynecological malignancy, with ~70% of patients diagnosed at advanced stages (5-year survival <30%) due to suboptimal early detection tools. Current modalities [e.g., carbohydrate antigen 125 (CA125), im…

This case report demonstrates the enhanced visualization capabilities of FAPI in visualizing deep infiltrating endometriosis (DIE) lesions compared to ultrasonography and MRI, suggesting its potential as a powerful diagnostic tool in the fu…

Ovarian response to controlled ovarian stimulation (COS) is a core determinant of assisted reproductive technology (ART) success, with marked interindividual variability. Accurate and individualized prediction is essential to optimize treat…

Pelvic inflammatory disease (PID), a prevalent gynecological ailment compromising women's health, demonstrates established risk mitigation from dietary trace minerals. However, iron's role in PID pathogenesis remains unestablished. The Nati…

ObjectiveThis study aimed to provide guidance for couples in dietary adjustments to optimize trace element concentrations for improved fertility and to offer a reference for formulating precise reproductive health policies.DesignIn this pro…

ObjectiveTo investigate the relationship between serum progesterone (P) on the day of embryo transfer (ET) and pregnancy outcomes in patients classified as POSEIDON Group 1.MethodsThis retrospective cohort study was conducted at the Reprodu…

ObjectiveTo investigate the association between the dynamic trajectories of urinary human chorionic gonadotropin (hCG) and the risk of early miscarriage after embryo transfer.MethodsIn this prospective cohort study conducted in Hebei Matern…

The rapid expansion and advancement of nanotechnology have presented potential applications in the diagnosis and treatment of various diseases. In recent years, cerium oxide nanoparticles (CeO2 NPs) have been extensively studied and applied…

BackgroundFirst-line treatment with non-steroidal anti-inflammatory drugs like ibuprofen for primary dysmenorrhea is effective for short-term pain relief but is often associated with a high recurrence of pain upon discontinuation. Tradition…

OBJECTIVE: Adenomyosis (AM) is a complex disease with poorly understood pathogenesis and considerable clinical phenotypic heterogeneity. Cluster analysis of coexisting diseases may help identify distinct clinical subtypes of AM and explore …

Poly (ADP-ribose) polymerase (PARP) inhibitors have emerged as a paradigm-shifting therapeutic strategy in oncology, demonstrating significant synthetic lethality in tumors characterized by homologous recombination deficiency. Due to their …

BACKGROUND: Catheter-associated urinary tract infections (CAUTIs) impose significant clinical and economic burdens on healthcare systems globally. Patients in obstetrics and gynecology face unique vulnerabilities; however, population-specif…

BackgroundTo compare the efficacy of modified gonadotropin-releasing hormone (GnRH) antagonist protocols combining clomiphene citrate (CC) or letrozole (LE) versus a conventional antagonist protocol in patients with normal ovarian reserve, …

Endometriosis is a prevalent chronic inflammatory gynecological disorder affecting approximately 10% of reproductive-age women worldwide, characterized by endometrial-like tissue outside the uterine cavity. Ectopic lesion growth tracks clos…

STUDY QUESTION: How can the potential mechanisms and targets of endometriosis be explored through multi-omics and multi-location approaches? SUMMARY ANSWER: This exploration of the gut-reproductive axis in patients with endometriosis found…

AbstractLow oocyte retrieval (LOR), defined as oocytes retrieved from <50% of mature follicles, significantly impacts IVF success, especially in patients with diminished ovarian reserve (DOR). Predictive models tailored for this population …

OBJECTIVE: This scoping review aimed to map the evidence on how digital health technologies are used for pain management in endometriosis. METHODS: This scoping review adhered to the Joanna Briggs Institute methodological framework and fol…

Systems biology is primarily concerned with the dynamic study of biochemical metabolic processes in physical systems, the interplay of multiple signal transduction routes, gene regulatory networks, and disease causes, among other things. It…

BACKGROUND: Recurrent implantation failure (RIF) is a major challenge in in vitro fertilization (IVF). The window of implantation (WOI) is the endometrium’s receptive period for embryos, and endometrial receptivity analysis (ERA) is a poten…

ObjectiveThe aim of this study was to compare the therapeutic efficacy of integrating virtual reality technology with conventional pelvic floor rehabilitation therapy versus conventional therapy alone in postpartum women with myofascial pel…

IntroductionAcupuncture has been explored as a potential intervention for POR; however, high-quality evidence is limited. This multicenter randomized trial evaluated the effect of acupuncture on the number of oocytes retrieved following con…