Ashok Agarwal

ORCID: 0000-0003-0585-1026 · 105 papers in corpus
review 2013
Minerva ginecologica

Increasing evidence suggests that female infertility is associated with endometriosis. Indeed, 40% of women with this disease are infertile. However, a causal relationship has not yet been established, and the possible pathophysiology of in…

review 2013
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-11-66

Approximately 10 to 15% of couples are impacted by infertility. Recently, the pivotal role that lifestyle factors play in the development of infertility has generated a considerable amount of interest. Lifestyle factors are the modifiable h…

review 2013
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113483018

The spindle apparatus is a vital structure and must be structurally intact for proper segregation of the oocyte's genetic material during metaphase II. Endometriosis, oxidative stress, and cryopreservation can all adversely affect the struc…

lab-animal 2012
·doi:10.1371/annotation/947afede-1969-4061-a535-164655e9de72

Interleukin 6 (IL-6) is considered a major indicator of the acute-phase inflammatory response. Endometriosis and pelvic inflammation, diseases that manifest elevated levels of IL-6, are commonly associated with higher infertility. However, …

nonrandomized-trial 2012
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2011.579652

OBJECTIVE: The purpose of this study was to evaluate the association between the follicular fluid (FF) reactive oxygen species (ROS) levels, total antioxidant capacity (TAC) and ROS-TAC score and pregnancy after intracytoplasmic sperm injec…

2012
·doi:10.1007/978-1-62703-041-0_9

Endometriosis is a chronic gynecologic disease process with multifactorial etiology. Increased oxidative stress, a result of increased production of free radicals or depletion of the body’s endogenous antioxidant defense, has been implicate…

observational 2012
·doi:10.3410/f.714597851.792002805

OBJECTIVE: To assess success rates of IVF and intracytoplasmic sperm injection in women with various stages of endometriosis.DESIGN: Retrospective cohort study.SETTING: Reproductive medicine unit in a university hospital.PATIENT(S): Inferti…

2012
·doi:10.3410/f.714597850.791352810
lab-animal 2012
PloS one ·doi:10.1371/journal.pone.0035535

Interleukin 6 (IL-6) is considered a major indicator of the acute-phase inflammatory response. Endometriosis and pelvic inflammation, diseases that manifest elevated levels of IL-6, are commonly associated with higher infertility. However, …

other 2012
Journal of molecular histology ·doi:10.1007/s10735-012-9454-7

Oxidative stress is associated with many disease states including gynecologic disease. This process can damage lipids, proteins and DNA. The present study highlights the role of oxidative stress induced DNA damage as measured by 8-hydroxy-2…

meta-analysis 2012
Revista da Associacao Medica Brasileira (1992) ·doi:10.1590/s0104-42302012000500020

Endometriosis, a highly prevalent gynecological disease, can lead to infertility in moderate to severe cases. Whether minimal stages are associated with infertility is still unclear. The purpose of this systematic review is to present studi…

meta-analysis 2012
·doi:10.1016/s2255-4823(12)70257-6

Endometriosis, a highly prevalent gynecological disease, can lead to infertility in moderate to severe cases. Whether minimal stages are associated with infertility is still unclear. The purpose of this systematic review is to present studi…

meta-analysis 2012
·doi:10.1016/s0104-4230(12)70257-9

Endometriosis, a highly prevalent gynecological disease, can lead to infertility in moderate to severe cases. Whether minimal stages are associated with infertility is still unclear. The purpose of this systematic review is to present studi…

review 2012
·doi:10.1586/eog.12.75

Ovarian endometrioma is a benign, estrogen-dependent cyst found in women of reproductive age. Infertility is associated with ovarian endometriomas; although the exact cause is unknown, oocyte quantity and quality are thought to be affected.…

2012
·doi:10.5005/jp/books/11630_37
meta-analysis 2012
Archives of gynecology and obstetrics ·doi:10.1007/s00404-012-2439-7

PURPOSE: Since the first description about oxygen toxicity made by Joseph Priestley, the oxidative stress has been enrolled as a key factor in the pathogenesis of endometriosis. Our aim was to review oxidative stress biomarkers measured in …

review 2012
·doi:10.1586/eog.12.19

Endometriosis is a known cause of infertility in reproductive-aged women. Most treatment plans target pain caused by the disease, and may overlook the possibility that the patient may want to conceive. This review assesses current studies o…

review 2012
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-10-49

Oxidative stress (OS), a state characterized by an imbalance between pro-oxidant molecules including reactive oxygen and nitrogen species, and antioxidant defenses, has been identified to play a key role in the pathogenesis of subfertility …

review 2011
·doi:10.1017/cbo9780511734755

Human Assisted Reproductive Technology: Future Trends in Laboratory and Clinical Practice offers a collection of concise, practical review articles on cutting-edge topics within reproductive medicine. Each article presents a balanced view o…

review 2011
Journal of oncology ·doi:10.1155/2011/475983

This paper reviews current screening techniques as well as novel biomarkers and their potential role in early detection of ovarian cancer. Ovarian cancer is one of the most common reproductive cancers and has the highest mortality rate amon…

review 2011
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-011-9608-7

Despite an ongoing debate over its efficacy, preimplantation genetic screening (PGS) is increasingly being used to detect numerical chromosomal abnormalities in embryos to improve implantation rates after IVF. The main indications for the u…

2010
·doi:10.1016/j.fertnstert.2010.07.786
nonrandomized-trial 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.09.043

OBJECTIVE: To examine the effect of peritoneal fluid (PF) of patients with endometriosis on the cytoskeleton of metaphase II oocytes and correlate the results with the stage of endometriosis and the duration of infertility. DESIGN: Prospec…

review 2010
·doi:10.2174/157340410791321381

Aim: Many studies have implicated oxidative stress in the pathogenesis of infertility causing diseases of the female reproductive tract. The aim of this study was to review the current literature on the effects of antioxidant therapy and to…

2010