J Julie Kim

No ORCID on file · 14 papers in corpus · active 2006-2023

Study types

  • article 6
  • review 5
  • other 2
  • book-chapter 1

Condition tags

  • endometriosis 14
  • infertility 2
article 2023
JCI insight ·doi:10.1172/jci.insight.160815

The development and progression of endometriotic lesions are poorly understood, but immune cell dysfunction and inflammation are closely associated with the pathophysiology of endometriosis. There is a need for 3D in vitro models to permit …

review 2017
Fertility and sterility ·doi:10.1016/j.fertnstert.2017.05.031
article 2016
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116632920
article 2014
Endocrinology ·doi:10.1210/en.2013-1951

The pathogenesis of endometriosis remains unclear, and relatively little is known about the mechanisms that promote establishment and survival of the disease. Previously, we demonstrated that v-akt murine thymoma viral oncogene homolog (AKT…

review 2014
Biology of reproduction ·doi:10.1095/biolreprod.114.119255

Progesterone plays an essential role in the maintenance of the endometrium; it prepares the endometrium for pregnancy, promotes decidualization, and inhibits estrogen-dependent proliferation. Progesterone function is often dysregulated in e…

other 2013
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2013-1661

CONTEXT: Endometriosis is characterized by progesterone resistance and hyperactivity of the AKT and MAPK pathways. Kinases can cause posttranslational modifications of the progesterone receptor (PR) to influence cellular localization and pr…

review 2013
Endocrine reviews ·doi:10.1210/er.2012-1043

Progesterone receptor (PR) mediates the actions of the ovarian steroid progesterone, which together with estradiol regulates gonadotropin secretion, prepares the endometrium for implantation, maintains pregnancy, and differentiates breast t…

article 2011
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2011-1527

CONTEXT: Endometriosis affects approximately 10% of women in the United States and causes pain and infertility. Decidualization of endometrial stromal cells from women with endometriosis is aberrant. OBJECTIVE: The objective of this study w…

book-chapter 2011
·doi:10.1210/endo-meetings.2011.part3.p17.p3-29
review 2010
Seminars in reproductive medicine ·doi:10.1055/s-0029-1242991

Loss of progesterone signaling in the endometrium may be a causal factor in the development of endometriosis, and progesterone resistance is commonly observed in women with this disease. In endometriotic stromal cells, the levels of progest…

other 2007
Molecular human reproduction ·doi:10.1093/molehr/gam005

Endometriosis is a poorly understood gynaecologic disorder that is associated with infertility. In this study, we examined the expression of HOXA10 in the eutopic endometrium of baboons with induced endometriosis. A decrease in HOXA10 mRNA …

article 2007
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719106298409
article 2007
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2006-0302

Local estrogen biosynthesis is a major factor in the pathogenesis of endometriosis. Aberrant expression of steroidogenic acute regulatory protein (StAR) and aromatase in endometriotic tissue leads to an up-regulation of estrogen production.…

review 2006
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2005.11.041

Endometriosis is the most common cause of pelvic pain and affects an estimated 5 million women in the US. The biologically active estrogen estradiol (E2) is the best-defined mitogen for the growth and inflammation processes in the ectopic e…