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Патогенетические особенности влияния дисбактериоза кишечника на развитие заболеваний женской репродуктивной системы до сих пор изучены недостаточно. Сегодня существует гипотеза, что дисбактериоз кишечника может иметь значение в этиопатоген…
Background. The term «endometriosis» implies the existence of viable tissue of ectopic endometrium in different anatomic locations outside the uterine cavity. The etiopathogenesis of this disease still remains a matter of debate, and one of…
The article describes such fundamental and applied aspects of pathogenesis and clinical manifestations of such rare disease as endometriosis of ureters. Frequent involvement of left ureter in its pelvic part, close to distal colon, associat…
Introduction. Macrophages are the center of homeostasis regulation in endometrioid heterotopia tissue. Being one of the most important elements in understanding the pathogenesis of endometriosis, macrophages control the changes in the coope…
Endometriosis nowadays still a disease with an undisclosed pathogenesis. This article demonstrates and explains the possibility of different variants of dissemination of endometrioid cells in the body with the formation of foci of extrageni…
This paper reveals the pathogenetic impact of the abnormal gut microbiota on the development of female reproductive system diseases. A dynamic imbalance between the altered microbiota and the macroorganism has many manifestations as hormona…
Background . According to modern knowledge, macrophages and platelets support the growth and development of endometrioid heterotopia, thereby maintaining its survival under unsuitable conditions. Objectives . To carry out a comparative anal…
Данная работа является попыткой прояснить роль эпителиально-мезенхимального перехода (ЭМП) в ткани эндометрия в норме, а также при эндометриозе. Рассмотрено значение ЭМП и обратного ему процесса мезенхимально-эпителиального перехода в восс…
Endometrioid heterotopia can have an adverse systemic effect on the organism through erythropoietin synthesis, which can affect erythropoiesis and reflect in blood analysis. The aim of the study was to investigate the effect of endometrioid…
The review describes the effect of certain hormones and their imbalance on apoptosis of retrogradely refluxed endometrial cells in the abdominal cavity and the effects of estrogen, progesterone, anti-Mullerian hormone, and gonadotropin-rele…
In this review, the stepwise mechanism of vascularization of retrogradely torn away endometrial tissue into the abdominal cavity during the formation of endometrioid heterotopy is described. The necessity of the formation of a specific micr…