Tsuyoshi Okuda

No ORCID on file · 4 papers in corpus · active 2003-2005

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 3
other 2005
Disappearance of steroid hormone dependency during malignant transformation of ovarian clear cell cancer
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/01.pgp.0000165173.90339.a2

Ovarian clear-cell carcinoma (OCCA) and ovarian endometrioid carcinoma (OEMC) are often associated with endometriosis. This study determined the immunohistochemical expression of steroid hormone receptors and cancer-related genes in OCCA an…

article 2004
K-ras mutation may promote carcinogenesis of endometriosis leading to ovarian clear cell carcinoma
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan ·doi:10.1007/s00795-004-0252-5

Endometriosis shares some features characteristic of malignancy; however, it remains unclear whether endometriosis is a precursor to malignant disease. The objective is to determine the genetic relationship between endometriosis and ovarian…

article 2004
Relationship between Malignant Transformation of Endometriosis and Genetic Alterations of K-ras and Microsatellite Instability
·doi:10.15369/sujms1989.16.47

Several genetic alterations have been associated with the malignant transformation from endometriosis to ovarian cancer. However, the role of each genetic alteration in this multi-step process of tumorigenesis has not been clarified. Region…

article 2003
p53 mutations and overexpression affect prognosis of ovarian endometrioid cancer but not clear cell cancer
Gynecologic oncology ·doi:10.1016/s0090-8258(02)00149-x

ObjectiveAlthough ovarian clear cell adenocarcinoma (OCCA) and ovarian endometrioid adenocarcinoma (EC) are considered to be closely related to endometriosis, the mechanisms of carcinogenesis of these two malignancies and malignant transfor…