Simone Ferrero

INTRODUCTION: The second-line treatment of endometriosis-related pain symptoms includes injectable depot formulations of gonadotropin-releasing hormone analogs (GnRH-as). These drugs improve the symptomatology by inducing a hypoestrogenic s…

Transvaginal ultrasonography (TVS) should be the first-line investigation in patients with suspicion of deep endometriosis and, in particular, of rectosigmoid endometriosis. TVS cannot assess the presence of intestinal nodules located proxi…

Abstract: Endometriosis recurrence after surgery is still an issue that afflicts the gynecologist. Adjuvant hormonal treatments have been suggested and approved in order to delay recurrence in symptoms and endometriotic lesions. The current…

therapeutic target for this benign hormone-dependent disease Further studies are needed to draw definitive conclusions on the relationship between endometriosis and vitamin D.

To assess the risk of rectal endometriosis persistence after laparoscopic shaving of rectovaginal nodules infiltrating the rectum. This prospective study included 68 patients who underwent shaving for rectovaginal nodules infiltrating the r…

Preoperative assessment of deep posterior endometriosis (DE) nodules is necessary to inform patients about the possible treatments and to provide informed consent in case of surgery. This study aims to investigate the accuracy of rectal wat…

To evaluate if tridimensional ultrasonography (3D-TVS) improves the performance of bidimensional ultrasonography (2D-TVS) in assessing the presence and characteristics of bladder endometriosis (BE). This prospective study included patients …

The objective of this study was to evaluate the performance of 3D rendering during rectal water contrast transvaginal ultrasonography (RWC-TVS) for estimating the bowel lumen stenosis caused by rectosigmoid endometriosis in comparison to co…

During pregnancy the appearance of endometriotic lesions may be impacted by changes in hormonal environment. This study aims to explore the impact of pregnancy on ultrasonographic features of deep endometriosis (DE) and endometriomas (OMA).…

Three-dimensional (3D) reconstructions may be employed during transvaginal rectal water-contrast transvaginal ultrasonography (RWC-TVS) to diagnose rectosigmoid endometriosis. This study aims to evaluate the influence of bowel preparation (…

To evaluate the accuracy of transvaginal ultrasonography (TVS) with or without three dimensional (3D) and high definition real time (HDLive) modalities in comparison to magnetic resonance imaging (MRI) in assessing deep myometrial and cervi…

This study compared the performance of bidimensional ultrasonography (2D-TVS) and three-dimensional automated volume calculation (SonoAVC) in calculating ovarian follicle count in patients with large endometriomas undergoing in vitro fertil…

INTRODUCTION: Endometriosis is a chronic benign estrogen-dependent disease characterized by the presence of endometriotic glands and stroma outside the uterine cavity. Although combined hormonal contraceptives and progestins, currently avai…

UNLABELLED: The focus of the presented work was to isolate and characterize circulating endometrial cells (CECs) enriched from peripheral blood (PB) of patients with diagnosed endometriosis. The molecular characteristics of CECs could be su…

Endometriosis is a chronic disease characterized by the growth of endometrial-like glands and stroma outside the uterine cavity. Nowadays, the exact etiology of endometriosis is unclear and the interaction between a variety of environmental…

First-line medical therapies for treating pain associated with endometriosis mainly consist in combined oral contraceptives and progestins. However, some women, having persistence of symptoms, may require further therapeutic options. Among …