Simone Ferrero

In conclusion, a high number of new investigational drugs targeting specific biological mechanisms have recently been proposed for treatment of endometriosis. Although the use of new hormonal treatments, such as GnRH-antagonists, is being d…

The primary objective of this study was to assess the changes in the ultrasonographic characteristic of endometriosis in patients undergoing long-term follow-up. The secondary outcome of the study was to assess the long-term impact of hormo…

The primary objective of this study was to evaluate the changes in the volume of rectosigmoid endometriotic nodules during treatment with dienogest (DNG). The secondary aim of the study was to assess the changes in pain and intestinal sympt…

To investigate the performance of transvaginal hysterosalpingo-contrast-sonography (HyCoSy) in assessing tubal patency in women with endometriosis. This study was based on the retrospective analysis of a prospectively collected database of …

Circulating placental growth factor (PlGF) levels are increased in women with endometriosis when compared with controls, conversely decreased levels of PlFG have been reported in pregnant women developing pre-eclampsia. For this reason, end…

This study aims to compare the performance of bidimensional rectal-water contrast-transvaginal ultrasonography (2D-RWC-TVS) with 3D-RWC-TVS for investigating the presence and characteristics of rectosigmoid endometriosis. This prospective s…

Endometriosis is a chronic disease characterized by the presence of hormone-responsive endometriotic glands and stroma outside the uterus that affect at least 4% of reproductive age women (1). It may be asymptomatic, but it frequently cause…

The non-surgical diagnosis of endometriosis is still challenging for the clinician. Ultrasonography and magnetic resonance imaging can be used to diagnose ovarian endometriotic cysts and deep infiltrating endometriosis; but their performanc…

Adenomyosis is a gynecologic disorder characterized by the presence of ectopic endometrial tissue within the uterine myometrium. It can involve most of the myometrium (diffuse adenomyosis), it may be present only in a circumscribed part of …

This study aimed to investigate the efficacy of the etonogestrel (ENG)-releasing implant in treating patients with rectovaginal endometriosis. The study was based on the retrospective analysis of a prospectively collected database, includin…

Publication in the conference proceedings of EUSIPCO, Bucharest, Romania, 2012

Endometriosis is a chronic benign disease that affects women of reproductive age. Medical therapy is often the first line of management for women with endometriosis in order to ameliorate symptoms or to prevent post-surgical disease recurre…

INTRODUCTION: Pharmacotherapy has a pivotal role in the management of endometriosis with long-term treatments balancing clinical efficacy (control of pain symptoms and prevention of recurrence of the disease after surgery) with an acceptabl…

INTRODUCTION: Endometriosis is a chronic estrogen and progestogen responsive inflammatory disease associated with pain symptoms and infertility. The medical therapy of endometriosis aims to induce decidualization within the hormonally depen…

OBJECTIVES: The primary objective of the study was to compare the performance of the rectal water transvaginal ultrasonography (RWC-TVS) with and without bowel preparation (BP) in diagnosing rectosigmoid endometriosis. The secondary objecti…

We read with great interest the article by Matsuzaki et al. (2018) entitled ‘In vitro and in vivo effects of MK2206 and chloroquine combination therapy on endometriosis: autophagy may be required for regrowth of endometriosis’ recently publ…

INTRODUCTION: Endometriosis is a hormone-dependent benign chronic disease that requires a chronic medical therapy. Although currently available drugs are efficacious in treating endometriosis-related pain, some women experience partial or n…