Keith Isaacson — Endo Lab

article 2002

Signal transduction pathways involved in macrophage migration induced by peritoneal fluid chemotactic factors in stages I and II endometriosis

Fertility and sterility ·doi:10.1016/s0015-0282(02)03130-8

ObjectiveTo explore the role of G-protein coupled signaling pathways in activation of macrophage migration in endometriosis stages I and II.DesignCase controlled study.SettingUniversity hospital.Patient(s)Fifteen patients undergoing laparos…

article 1999

Effect of a baseline ovarian cyst on the outcome of in vitro fertilization–embryo transfer

·doi:10.1016/s0015-0282(98)00449-x

ObjectiveTo determine the significance of prestimulation ovarian cysts on the response to controlled ovarian hyperstimulation and the outcome of IVF.DesignRetrospective study.SettingIn vitro fertilization unit in an academic center.Patient(…

article 1999

P-164. The SCID (severe combined immunodeficiency) mouse: an experimental model for endometriosis

·doi:10.1093/humrep/14.suppl_3.223

article 1999

The SCID mouse: an experimental model for endometriosis

Human Reproduction ·doi:10.1093/humrep/14.12.3107

The purpose of this study was to validate the suitability of the severe combined immunodeficient (SCID) mouse as an experimental model for endometriosis, by defining the morphological and histological features of induced endometrial implant…

article 1998

Impact of Varying Stages of Endometriosis on the Outcome of In Vitro Fertilization–Embryo Transfer

Journal of assisted reproduction and genetics ·doi:10.1023/a:1022574221115

PurposeThe impact of severity of endometriosis on the outcome of in vitro fertilization (IVF) was analyzed in an uncontrolled, retrospective study in an academic IVF program.MethodsSixty-one patients with a primary diagnosis of endometriosi…

article 1997

Increased expression of complement component 3 in human ectopic endometrium compared with the matched eutopic endometrium

Fertility and sterility ·doi:10.1016/s0015-0282(97)00254-9

ObjectiveTo compare the gene expression of complement component 3 (C3) in human eutopic and ectopic endometrium.DesignA prospective, controlled study.SettingAcademic hospital.Patient(s)Women with documented endometriosis.Intervention(s)Euto…

article 1997

P-071 Expression of members of the Bcl-2 gene family and the relationship with apoptosis in endometriosis

·doi:10.1016/s0015-0282(97)90887-6

article 1995

Target Antigen(s) in Endometrial Autoimmunity of Endometriosis

Autoimmunity ·doi:10.3109/08916939508995698

OBJECTIVE: To obtain the molecular weights (MW) of endometrial antigens eliciting immunoglobulin (Ig) G auto-antibodies in all endometriosis patients irrespective of their place of origin or race, and to verify their specificity and immunog…

review 1994

Comparative study of different laser systems

·doi:10.1016/s0015-0282(16)56629-1

ObjectiveTo review lasers, laser physics, laser-tissue interaction, delivery systems, and their clinical applications relevant to gynecology.SettingsGynecological Service at Massachusetts General Hospital (MGH) and MGH Laser Center.Interven…

article 1991

The effect of estradiol on the production and secretion of complement component 3 by the rat uterus and surgically induced endometriotic tissue

Fertility and sterility ·doi:10.1016/s0015-0282(16)54135-1

We have recently demonstrated that glandular epithelial cells isolated from human endometriotic tissue synthesize and secrete complement component 3 (C3). Furthermore, because C3 is capable of producing many of the immunological activities …

article 1989

Production and Secretion of Complement Component 3 by Endometriotic Tissue*

The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem-69-5-1003

Many investigators have described a variety of immune phenomena associated with endometriosis. Among these are elevated titers of activated macrophages, monokines, and lymphokines in the peritoneal fluid of patients with endometriosis. In 1…