Adam Auton

No ORCID on file · 5 papers in corpus · active 2019-2024

Study types

  • review 2
  • article 1
  • erratum 1

Condition tags

  • endometriosis 4
2024
Evaluating genetically-predicted causal effects of lipoprotein(a) in human diseases: a phenome-wide Mendelian randomization study
·doi:10.1101/2024.07.24.24310950

Background Lipoprotein(a) (Lp[a]) is a circulating plasma lipoprotein that is emerging as an important independent risk factor for vascular disease. Lp(a) levels are 75-90% heritable, predominantly determined by copy number variation and s…

erratum 2022
Author Correction: Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
Nature communications ·doi:10.1038/s41467-022-33222-y
review 2021
Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways
Human Reproduction ·doi:10.1093/humrep/deab254

STUDY QUESTION: Is there a shared genetic or causal association of endometriosis with asthma or what biological mechanisms may underlie their potential relationships? SUMMARY ANSWER: Our results confirm a significant but non-causal associat…

article 2020
Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality
Human genetics ·doi:10.1007/s00439-020-02223-6

Evidence from observational studies indicates that endometriosis and depression often co-occur. However, conflicting evidence exists, and the etiology as well as biological mechanisms underlying their comorbidity remain unknown. Utilizing g…

review 2019
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
Nature communications ·doi:10.1038/s41467-019-12536-4

Abstract Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract and primary cause for hysterectomy, leading to considerable morbidity and high economic burden. Here we conduct a GWAS meta-analysis in 35,474 …