Xu KH

OBJECTIVE: To assess the efficacy and safety of Sanjie Analgesic Capsule (SAC) in Chinese patients with endometriosis-associated pain. METHODS: This was a multicenter, randomized, double-blind, placebo-controlled trial conducted at 15 cent…

OBJECTIVE: To investigate the effect of aquaporin 5(AQP5) on proliferation and migration of ectopic endometrial epithelial cells. METHODS: AQP5 shRNA interference fragments were designed and transfected into ectopic endometrial epithelial c…

Aquaporin 5 (AQP5) participates in the migration of endometrial cells. Elucidation of the molecular mechanisms associated with AQP5-mediated, migration of endometrial cells may contribute to a better understanding of endometriosis. Our obje…

Aquaporin (AQP)-dependent cell migration has broad implications in angiogenesis, tumor metastasis, wound healing, glial scarring and other events requiring cell movement. There are 13 isoforms of AQP (0-12) that have been identified in mamm…

OBJECTIVE: To investigate the effect of mifepristone on the expression of Caspase-3 in the granulosa cells. METHODS: Forty Sprague-Dawley (SD) female rats with (230 +/- 20) g weight were divided into four groups, low-dose group with 1.04 mg…

OBJECTIVE: To evaluate the effects of PRL-3 siRNA (small interfering RNA) on the migration of endometriotic stromal cells. METHODS: Primary endometriotic stromal cells were cultured in vitro. Then PRL-3 (phosphatase of regenerating liver-3…

ObjectiveTo investigate the expression of phosphatase of regenerating liver-3 (PRL-3) in ectopic, eutopic, and normal endometria and explore its relationship with endometriosis.DesignA clinical retrospective and molecular study.SettingDepar…

ObjectiveTo investigate the expression of aquaporin (AQP) in eutopic and ectopic endometrial tissues from women with endometriomas.DesignControlled laboratory research.SettingHospital-based unit for gynecology and obstetrics and research la…