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Endometriosis (EM) is a common gynecological disease. Though m6A RNA methylation has emerged as a key regulator in various physiological and pathological processes, its cell-type-specific function in EM remains unclear. We obtain batch and …
Abstract A healthy endometrium is crucial for embryo implantation and pregnancy maintenance. Thin endometrium, reduced glands and fibrosis resulting from infection or mechanical injury, are the primary causes of long-term infertility and po…
Endometrial tolerance is a key factor for successful embryo implantation and endometrial thickness is an important clinical indicator for its evaluation. The incidence of thin endometrium in IVF is 2.4%, and most studies have shown that cli…
PROBLEM: Endometriosis (EMS) is an estrogen-dependent disease which is characterized with estrogen-dependent growth of ectopic endometrium and increased local estrogen production. EMS performs tumor-like biological functions such as invasiv…
Background.In the bone marrow microenvironment of postmenopausal osteoporosis (PMOP), bone marrow mesenchymal stem cell (BMSC)-derived exosomal miRNAs play an important role in bone formation and bone resorption, although the pathogenesis h…
ICG fluorescence visualization could conduct accurate resection of AWE, which is clinically safe and effective.
Endometriosis is a chronic inflammatory disease characterized by the elevation of proinflammatory cytokines, such as IL-6, in the peritoneal fluid. However, the precise mechanism of the highly elevated IL-6 levels in ectopic milieu remains …
PROBLEM: Chemokines have been reported to play a sovereign role in the establishment and progression of endometriosis. Fractalkine is a chemokine that is upregulated in many inflammatory diseases including endometriosis. Fractalkine functio…
O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide ass…
OBJECTIVE: To investigate the incidence, influencing factors and intervention of gestrinone-related abnormal uterine bleeding at different dosage of gestrinone in the clinical treatment. METHODS: This was a multicenter, randomized, control…
BACKGROUND: The study was performed to characterize and compare the serum lipid profile in gynecologic cancers and benign diseases. MATERIALS AND METHODS: A total of 1,550 age-matched females were included in this study: 760 patients with g…
OBJECTIVE: To study the possibility of a correlation between polymorphism of human leukocyte antigen (HLA)-I antigen and occurrence of endometriosis (Em). METHODS: Polymorphism of HLA-I A and B locations were detected by mini-lymphocytotoxi…
OBJECTIVE: To investigate the abnormal distribution of lymphocytes in eutopic and ectopic endometrium of patients with endometriosis and its significance. METHODS: In 43 cases, biopsies of ectopic tissues were taken by laparoscopy and lapar…