Huang G

RESEARCH QUESTION: What is the impact of focal adenomyosis on IVF/iICSI outcomes, and what is the optimal protocol for these patients? DESIGN: This retrospective study screened 66,711 first IVF/ICSI cycles and identified 598 women with foc…

BACKGROUNDS: Abnormal cleavage (ABNCL) in early human embryos is a frequent phenomenon associated with impaired developmental competence and reduced reproductive potential. However, the clinical determinants of ABNCL and its subtypes remain…

This study aimed to investigate how levels of serum follicle-stimulating hormone (FSH) on Day 7 of ovarian stimulation are related to the number of oocytes retrieved, and identify any cutoff or threshold point in protocols using gonadotropi…

Poor ovarian response (POR) constitutes a notable clinical challenge within the domain of assisted reproductive technology, primarily attributable to the lack of reliable biomarkers for precise diagnosis and treatment. This study reveals si…

BackgroundEndometrial receptivity in hormone replacement therapy-frozen embryo transfer (HRT-FET) cycles depends on a precisely coordinated estradiol-progesterone environment. An imbalance between estradiol (E2) and progesterone (P) before …

Endometritis is a common inflammatory disorder of the female reproductive tract caused by microbial infection or immune dysregulation that impairs endometrial function and reproductive outcomes. Growing evidence indicates that programmed ce…

The extraction methods of berberine hydrochloride include water, acidified water, lime milk, and ethanol extraction. The water extraction method is mainly a decoction method, whereas the alcohol extraction method mainly includes microwave, …

The study aimed to investigate the expression of nuclear actor-k-gene binding(NF-κB) and immediate early response 3(IER3) in ovarian endometrioid cysts and its correlation with the recurrence of the ovarian endometrioid cyst. From January 2…

BackgroundThe principal indicators adopted for the assessment of follicular quality are still two-dimensional ultrasound(2D-US) imaging parameters, but these do not reflect the three-dimensional morphology of follicles. We herein aimed to e…

Thin endometrium (TE, ≤7 mm) is widely recognized as a critical cause of infertility, recurrent pregnancy losses, and placental abnormalities. Granulocyte-macrophage colony-stimulating factor (GM-CSF) plays a crucial role in tissue repair, …

BackgroundAbdominal ectopic pregnancy is a rare form of ectopic pregnancy, and diaphragmatic ectopic pregnancy is even rarer. We described a case of an ectopic pregnancy implanted on the diaphragm's surface, diagnosed using multimodality im…

ObjectivesTo analyze clinical outcomes and the factors that influence the therapeutic outcomes of high-intensity focused ultrasound (HIFU) ablation for different types of submucosal uterine fibroids.Materials and methodsA total of 626 patie…

Female adnexal malignancies, while relatively uncommon, exhibit high mortality rates due to often-late diagnosis. The serine/threonine kinase 11 (STK11) is a tumor suppressor gene, and its inactivation or mutation often leads to an autosoma…

ObjectiveTo analyze the clinical characteristics of scar cancer ulcer wound of head and face, and to investigate its diagnosis and treatment.MethodsThe clinical data of 14 patients with head and facial scar cancer ulcer wounds who met the s…

BackgroundExercise is increasingly being promoted as an effective treatment for primary dysmenorrhea (PD). This study aims to conduct a comprehensive network meta-analysis (NMA) of randomized controlled trials to identify the optimal types …

PurposeZygotes with 2.1 pronuclei (2.1PN) present with two normal-sized pronuclei, and an additional smaller pronucleus, that is approximately smaller than two thirds the size of a normal pronucleus. It remains unclear whether the additiona…

ObjectiveThe objective of this retrospective cohort study is to investigate the impact of monitoring serum estradiol (E2) levels before progesterone administration within hormone replacement therapy (HRT) on pregnancy outcomes in women unde…

Abstract Background In the realm of immunological disorders, allergic rhinitis (AR) persists as a prevalent condition, yet its molecular underpinnings remain only partially deciphered, necessitating deeper exploration. This study pioneers …

Perfluoroalkyl and polyfluoroalkyl substances (PFASs), widely utilized in various industries, may pose potential reproductive well-being risks. However, the research on the impact of PFAS exposures on pregnancy and live birth rates remains …

PurposeWe aimed to compare the DNA methylation profiles of human embryos cultured in uninterrupted or interrupted incubators.MethodsThis study included 9 women, ≤ 30 years old (range: 20-30 years), without a history of genetic diseases or s…

Cystic adenomyosis is a rare type of uterine adenomyosis, mainly seen in young women, which is often characterized by severe dysmenorrhea. The quality of life and reproductive function of young women could be affected by misdiagnosis and de…

ObjectivesTo investigate changes in brain-glucose metabolism in anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, and compare results with MRI and electroencephalography (EEG) findings at different disease stages.MethodsThe clinical …

This study was to evaluate whether Intracytoplasmic sperm injection (ICSI) can improve the quality of embryo in patients with poor-quality embryos in the previous In-vitro fertilization (IVF) cycle, which was cancelled before transfer. This…

BackgroundInfertility is estimated to occur in 1 out of every 4-7 couples. Intracytoplasmic sperm injection (ICSI), a type of assisted reproduction introduced in 1992, has been used across the world for almost all indications of infertility…