Stefan P Renner

Objective The objective of this revised official guideline, published by the German Society for Gynecology and Obstetrics (DGGG) and coordinated in the joint guidelines program of the DGGG, the Austrian Society for Gynecology and Obstetrics…

STUDY QUESTION: Was the efficacy of linzagolix, observed at 6 months in women with endometriosis-associated pain, maintained when administered for an additional 6 months? SUMMARY ANSWER: Efficacy from this extension study complements the r…

PURPOSE: Endometriosis appears in various forms and symptoms. With regard to the established endometriosis classifications, it is hardly possible to draw conclusions from the endometriosis to the symptoms caused by it. The objective of this…

BACKGROUND/AIM: Adenomyosis is a common gynecological disease characterized by the presence of ectopic endometrial tissue (endometrial stroma and glands) within the myometrium. It is classified into two main types: diffuse and focal. The ai…

PURPOSE OF REVIEW: Endometriosis is a chronic inflammatory condition that significantly affects women's quality of life and fertility. Despite advancements in treatment, many areas of uncertainty persist in clinical management. This review …

With a growing number of women in developed countries having children later in life, it is time to rethink women's reproductive health. This trend of 'delayed parenthood' reflects a complex interplay of labour market rules, personal choices…

STUDY QUESTION: Does linzagolix administered orally once daily for up to 3 months at a dose of 75 mg alone or 200 mg in combination with add-back therapy (ABT) (1.0 mg estradiol; 0.5 mg norethindrone acetate, also known as norethisterone ac…

Abstract Study question Does once-daily linzagolix taken up to 12 months maintain pain reduction observed at 6 months in women with endometriosis? Summary answer Linzagolix alone or in combination with combined add-back therapy (ABT) for 12…

Die Therapie der Endometriose richtet sich unter anderem nach dem Ausmaß der Symptomatik, dem aktuellen bzw. dem zukünftigen Kinderwunsch sowie dem Alter der Patientin. Therapieoptionen sind die medikamentöse, die operative sowie die Schmer…

OBJECTIVE: To evaluate blood-based biomarkers to detect endometriosis and/or adenomyosis across nine European centers (June 2014-April 2018). METHODS: This prospective, non-interventional study assessed the diagnostic accuracy of 54 blood-…

Abstract Aims The aim of this official guideline published and coordinated by the German Society of Gynaecology and Obstetrics (DGGG) in cooperation with the Austrian Society for Gynaecology and Obstetrics (OEGGG) and the Swiss Society for …

Einleitung: Die Endometriose ist mit ihren vielseitigen Erscheinungsformen ein Chamäleon unter den Erkrankungen. Eine eindeutige Ätiologie ist bislang nicht bekannt und die Heterogenität der klinischen Symptomatik erschwert die frühzeitige …

ObjectiveTo analyze preoperative and postoperative sexual function following surgery for deeply infiltrating endometriosis (DIE) with and without bowel involvement.Study designPatients with DIE who underwent surgery between 2001 and 2011 wi…

(P = 0.008) and magnesium (P = 0.043) compared to controls. This study confirms a high association of endometriosis and gastrointestinal disorders accompanied by an altered nutrient intake. A dietary intervention by a professional nutrition…

Endometriosis is one of the most common benign gynecological diseases. The extremely heterogeneous complex of symptoms complicates the diagnosis and treatment of this disease. In most patients, there is a latency period of several years bet…

It is known that endometriosis is associated with an increased risk for certain forms of ovarian cancer. However it is unknown, which kind of endometriosis is associated with ovarian cancer and furthermore, if endometriosis is associated wi…

Sowohl für das Ovarialkarzinom als auch für Endometriose sind genetische Varianten als Risikofaktoren validiert. Endometriose ist als Risikofaktor für das klarzellige, das endometrioide und das low grade seröse Ovarialkarzinom beschrieben. …

Several genetic variants have been validated as risk factors for endometriosis, endometrial and ovarian cancer. Endometriosis has also been described as a risk factor for endometrial and ovarian cancer. The aim of the present study was to t…

PurposeTo analyze major and minor complications following surgery for deeply infiltrating endometriosis including long-term impairment of intestinal, bladder, and sexual function.MethodsPatients who had undergone resection for deeply infilt…

Symptome und Ausprägung einer Endometrioseerkrankung können vielschichtig sein. Therapeutisch steht die operative Resektion der Endometrioseläsionen im Vordergrund. Prä- und postoperativ ist eine medikamentöse Therapie zu diskutieren, in in…

ObjectiveSeveral genetic variants have been validated as risk factors for ovarian cancer. Endometriosis has also been described as a risk factor for ovarian cancer. Identifying genetic risk factors that are common to the two diseases might …

PurposeThe aim of the present study was to analyze major and minor complications-including long-term impairment of intestinal, bladder, and sexual function-following surgery for deeply infiltrating endometriosis using anterior rectal resect…

STUDY QUESTION: Which essential items should be recorded before, during and after endometriosis surgery and in clinical outcome based surgical trials in patients with deep endometriosis (DE)? SUMMARY ANSWER: A DE surgical sheet (DESS) was …