Granne I

No ORCID on file · 14 papers in corpus · active 2018-2024

Study types

  • other 2
  • article 1
  • preprint 1
  • review 1

Condition tags

  • endometriosis 5
  • infertility 2
  • chronic_pelvic_pain 1
article 2024
Nature genetics ·doi:10.1038/s41588-024-01873-w

The complex and dynamic cellular composition of the human endometrium remains poorly understood. Previous endometrial single-cell atlases profiled few donors and lacked consensus in defining cell types. We introduce the Human Endometrial Ce…

preprint 2023
·doi:10.1101/2023.11.03.564728

Abstract The human endometrium, the inner lining of the uterus, exhibits complex, dynamic changes throughout the menstrual cycle in response to ovarian hormones. Aberrant response of endometrial cells to hormones is associated with multiple…

review 2023
Frontiers in immunology ·doi:10.3389/fimmu.2023.1225639

BACKGROUND: Endometriosis is a chronic disease affecting 6-10% of women of reproductive age. It is an important cause of infertility and chronic pelvic pain with poorly understood aetiology. CD8+ T (CD8 T) cells were shown to be linked to i…

2022
Mucosal immunology ·doi:10.1038/s41385-021-00451-1

Recurrent Pregnancy Loss (RPL) affects 2-4% of couples, and with increasing numbers of pregnancy losses the risk of miscarrying a euploid pregnancy is increased, suggesting RPL is a pathology distinct from sporadic miscarriage that is due l…

2022
PLoS medicine ·doi:10.1371/journal.pmed.1004095

[This corrects the article DOI: 10.1371/journal.pmed.1003679.].

2021
Frontiers in cell and developmental biology ·doi:10.3389/fcell.2021.709280

The human endometrium is the innermost mucosal membrane of the uterus and is the first point of contact for an implanting blastocyst. A wide variety of immune cells are found amongst the endometrial epithelial layers and stromal cells which…

2021
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deab043
2021
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deab044
2021
·doi:10.1101/2021.06.01.21257781

Background Obesity is observationally associated with altered risk of many female reproductive conditions. These include polycystic ovary syndrome (PCOS), abnormal uterine bleeding, endometriosis, infertility, and pregnancy-related disorder…

other 2020
Human Reproduction ·doi:10.1093/humrep/dez301

STUDY QUESTION: Does the method of fertilisation improve reproductive outcomes in poor ovarian response (POR) cycles when compared to all other ovarian response categories in the absence of male factor subfertility? SUMMARY ANSWER: ICSI do…

2020
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deaa243

Study questionCan consensus definitions for the core outcome set for infertility be identified in order to recommend a standardized approach to reporting?Summary answerConsensus definitions for individual core outcomes, contextual statement…

2020
Nature communications ·doi:10.1038/s41467-020-19742-5

Miscarriage is a common, complex trait affecting ~15% of clinically confirmed pregnancies. Here we present the results of large-scale genetic association analyses with 69,054 cases from five different ancestries for sporadic miscarriage, 75…

other 2019
Human reproduction open ·doi:10.1093/hropen/hoz020

STUDY QUESTION: Does ART impact the secondary sex ratio (SSR) when compared to natural conception? SUMMARY ANSWER: IVF and ICSI as well as the stage of embryo transfer does impact the overall SSR. WHAT IS KNOWN ALREADY: The World Health O…

2018
Human molecular genetics ·doi:10.1093/hmg/ddy317

The normal menstrual cycle requires a delicate interplay between the hypothalamus, pituitary and ovary. Therefore, its length is an important indicator of female reproductive health. Menstrual cycle length has been shown to be partially con…