Bai X

OBJECTIVE: To assess the pre-treatment severity of adenomyosis and compare the effectiveness of the levonorgestrel-releasing intrauterine system (LNG-IUS) with that of dienogest (DNG) over various follow-up periods. DATA SOURCES: We used a…

ObjectTo evaluate the association between hysterectomy and the risk of developing urinary incontinence (UI) based on observational studies.MethodsWe conducted a systematic search of PubMed, Embase, and Cochrane Library for observational stu…

ObjectiveThe aim of this study was to comparatively analyze the therapeutic effects of uterine artery embolization (UAE) and laparoscopic myomectomy (LM) on uterine fibroids to determine which treatment method is more beneficial for patient…

Fertility in women decreases with age, but the molecular basis for age-related, unexplained infertility remains elusive. Here, we reveal distinct transcriptome changes in oocytes and surrounding cumulus cells from women in their mid-thirtie…

BACKGROUND: This study aimed to assess how embolization endpoints affect the efficacy of uterine artery embolization (UAE) for adenomyosis. METHODS: In this single-center retrospective cohort study, patients treated with UAE from 2014-2018…

ContextPolycystic ovary syndrome (PCOS), a common endocrine disorder in women of reproductive age, is closely associated with chronic low-grade inflammation and metabolic disturbances. In PCOS mice, dietary inulin has been demonstrated to r…

BackgroundPolycystic ovary syndrome (PCOS) is the main cause of anovulatory infertility in women of reproductive age, and low-grade chronic inflammation plays a key role in the occurrence and development of PCOS. However, obesity, as a like…

PURPOSE: We aimed to develop and validate a predictive score to estimate the post-operative recurrence risk after laparoscopic excision of ovarian endometrioma (OMA). PATIENTS AND METHODS: The prediction score was developed using a training…

The vaginal microbiome plays an essential role in the reproductive health of human females. As infertility increases worldwide, understanding the roles that the vaginal microbiome may have in infertility and in vitro fertilization (IVF) tre…

Abstract China’s “three-child policy” in response to population ageing has cast safeguarding perinatal health an urgent priority, whereas previous research seldom explored the pregnancy-related cardiovascular and haematological diseases. H…

AimTo compare the pregnancy outcomes of frozen-thawed embryo transfer (FET) cycles among women with repeated implantation failure (RIF) treated with various endometrial preparation protocols.MethodsA total of 605 women with RIF were retrosp…

BackgroupFrozen-thawed embryo transfer is rising worldwide. One adverse effect of programmed frozen embryo transfer (FET) reported in some studies is an increased risk of adverse obstetric and perinatal outcomes. Meanwhile, body mass index …

Premature ovarian failure (POF) is a multifactorial disease that refers to the occurrence of secondary amenorrhea, estrogen decrease, and gonadotropin increase in women under the age of 40. The prevalence of POF is increasing year by year, …

Inositol 1,4,5-Triphosphate Receptor Family (ITPRs) are necessary intracellular Ca2+-release channel encoders and participate in mammalian cell physiological and pathological processes. Previous studies have suggested that ITPRs participate…

BackgroundThe purpose of this study was to assess the risk factors for cholesterol polyp formation in the gallbladder.MethodsThis was a multicenter retrospective study based on pathology. From January 2016 to December 2019, patients who und…

OBJECTIVES: Adenomyosis is a common and refractory disease in gynecology. Preserving the uterus during treatment for adenomyosis remains a problem. High-intensity focused ultrasound (HIFU) is widely used in treatment of solid tumors. This s…

Little is known about the genetic alterations characteristic of ovarian clear cell carcinoma (OCCC). Our aim was to identify targetable genomic alterations in this type of cancer. Forty-two OCCC formalin-fixed, paraffin-embedded (FFPE) tiss…

Research questionUsing RNA-sequencing analysis, we investigated the relationship between ovarian stimulation and endometrial transcriptome profiles during the window of implantation (WOI) to identify candidate predictive factors for the WOI…