Hye Won Chung

Abstract To investigate the role of robotic single-site (RSS) ovarian cystectomy in fertility preservation, which was compared with single-port laparoscopic (SPL) surgery based on AMH changes. We retrospectively analyzed medical records of …

OBJECTIVE: Endometriosis is a common and recurring gynecologic disease which have afflicting females of reproductive age. We investigated the efficacy of long-term, post-operative use of dienogest for ovarian endometrioma. METHODS: We studi…

OBJECTIVES: To evaluate preoperative anti-Müllerian hormone (AMH) levels in women with endometrioma or other benign ovarian cysts and differences of AMH changes according to various characteristics. METHODS: Ninety-seven patients aged 20 to…

PROBLEM: To characterize the genetic variation across the MMP-2 and TIMP-2 gene with the risk of advanced-stage endometriosis. METHOD OF STUDY: Ten single-nucleotide polymorphisms (SNPs) and haplotype associations between MMP-2 (9082A>G, 91…

To investigate the characteristics and to define the most effective diagnosis and treatment option for the scar endometriosis resulting from abdominal incision or episiotomy.

Endometriosis, one of the most common gynecologic disorders, is broadly defi ned as the presence of endometrial glandular and stromal cells outside the uterine cavity, associated with symptoms of dysmenorrhea, dyspaureunia, chronic pelvic p…

OBJECTIVE: To investigate whether the -1562C>T, R279Q, P574R, and R668Q polymorphisms of the matrix metalloproteinase-9 (MMP-9) gene are related to endometriosis. DESIGN: Case-control study. SETTING: University-based hospital in Korea. P…

목적: 자궁내막증은 자궁 밖의 다른 조직, 특히 복막, 난소, 직장질격막 등에 샘과 버팀질을 포함한 기능성의 자궁내막조직이 존재하는 질환을 말한다. 정확한 병인은 알려지지 않고 있지만 생리 중 역류한 자궁혈이 자궁 외 조직에 착상해 발생하는 것으로 생각되며 이 과정에는 혈관내피세포성장인자 (vascular endothelial cell growth factor, VEGF)가 중요한 역할을 하고 있는 것으로 보인다. 본 연구는 …

A variety of factors affect the development of endometriosis, including hormonal status and genetic factors. The growth of endometriosis is stimulated by local estrogen production in conjunction with circulating estrogen. The CYP19 gene enc…

Endometriosis is one of the most common gynaecological disorders, but its aetiology and pathogenesis remain obscure. The refluxed menstrual debris in women with endometriosis may be more prone to implantation, invasion and growth in the per…

Objective: To investigate whether polymorphism of CYP17 gene is associated with the risk of advanced endometriosis in Korean women. Methods: The 194 endometriosis patients and 209 controls were enrolled. Blood samples were collected from 19…

Endometriosis, one of the most common gynaecologic disorders, shows significantly elevated prevalence in industrial areas and there is also a possible genetic predisposition. Glutathione-S-transferases (GSTs) are enzymes involved in the met…

Objective To investigate whether polymorphism of gene encoding estrogen receptor-α is associated with the risk of endometriosis in Korean women. Material and Methods We investigated 136 patients with histopathologically confirmed endometrio…

Objective : Enzymes belonging to the Glutathione S transferase and cytochrome P450 families are involved in the two-stage detoxification process of a number of pro-carcinogens. We genotyped each 74 women with moderate or severe endometriosi…

Objective : The aim of this study was to examine whether polymorphic variation in GSTs confers susceptibility to Endometriosis in Korean populations. Methods : The GSTM1, GSTT1, and GSTP1 genotypes were determined in 124 patients with Endom…

Endometriosis is characterized by the ectopic implantation of endometrium on peritoneal surfaces. Angiogenic and growth factors may play a significant role in the pathogenesis of endometriosis. Midkine (MK) and pleiotrophin (PTN) are two re…

The diagnosis of cervical incompetency is routinely accomplished by reviewing the clinical history and pelvic examination subjectively. Rescently by using ultrasonography. the objective method in diagnosis of cervical incompetency was devel…