Maria Grazia Porpora

INTRODUCTION: Endometriosis is a chronic inflammatory disease that affects approximately 10% of women of reproductive age. Its clinical manifestations are highly heterogeneous, but pelvic pain is the most frequent, causing functional disabi…

Structured reporting systems for endometriotic disease are gaining a central role in diagnostic imaging: our aim is to evaluate applicability and the feasibility of the recent ENZIAN score (2020) assessed by MRI. A total of 60 patients with…

Objective Combined oral contraceptives (COC) and progestogens are widely used for the treatment of endometriosis. The objective of the study is to compare the efficacy of dienogest 2 mg vs continuous oral levonorgestrel/EE (levonorgestrel 0…

Endometriosis is a gynecological estrogen-dependent disease whose commonest pain symptoms are dysmenorrhea, dyspareunia, and acyclic chronic pelvic pain (CPP). Hormonal changes occurring during breastfeeding seem to reduce pain and disease …

Endometriosis is a chronic, benign, gynecological disorder characterized by the presence of ectopic \nendometrial tissue outside the uterine cavity, affecting up to 10% of women of reproductive age. Endometriosis is a complex and heterogene…

BACKGROUND: Adenomyosis has been considered for a long time a condition of advanced reproductive age. Recently, imaging techniques have allowed its diagnosis in young women. The aim of our study was to compare adenomyosis in early (18-35) a…

Endometriosis and pelvic pain are associated. However, only half of the subtle and typical, and not all cystic and deep lesions are painful. The mechanism of the pain is explained by cyclical trauma and repair, an inflammatory reaction, act…

Endometriosis may compromise the physiological course of pregnancy. The aim of this prospective observational study was to evaluate whether endometriosis causes a higher prevalence of obstetric and neonatal complications as well as a higher…

Objectives The aim of this study was to explore whether women with endometriosis-related infertility had poorer psychological, sexual and relational scores compared with endometriosis without infertility. Methods Seventy-one endometriosis w…

Alimentary nickel (Ni) may result in allergic contact mucositis (ACM), whose prevalence is >30% and may present with IBS-like and extra-intestinal symptoms. These symptoms are also frequent in endometriosis, and Ni allergic contact dermatit…

BACKGROUND: Endometriosis is a widespread multifactorial disease in which environmental, genetic, and epigenetic factors contribute to the phenotype. Single Nucleotide Polymorphisms (SNPs) in genes implicated in pivotal molecular mechanisms…

The incidence of endometriosis in middle-aged women is not minimal compared to that in the reproductive age group. The treatment of affected women after childbearing age to the natural transition toward menopause has received considerably p…

The immune system seems to be involved in the pathogenesis of endometriosis. Peritoneal chronic inflammation is present and natural killer cells and macrophages abnormalities have been reported in women with the disease. Moreover, a higher …

Endometriosis is a gynecological condition often associated with genito-pelvic pain. Psycho-emotional factors, such as lack of emotional awareness and/or presence of negative emotions, have an important role on sexual dysfunctions. These fa…

Objective Endometriosis is a chronic condition frequently characterized by genito-pelvic pain. Sexual and relational impairments in women with this condition are largely reported in literature. No prior study, at our knowledge, focused on t…

The protective effect of pregnancy on endometriosis is well known, but complications related to the pregnant state, such as hemoperitoneum, uroperitoneum and bowel perforation may occur.

A network of endometriosis experts from 16 Italian academic departments and teaching hospitals distributed all over the country made a critical appraisal of the available evidence and definition of 10 suggestions regarding measures to be de…

DSM 5 collects in the category “Genito-Pelvic Pain/Penetration disorder (GPPPD)” some clinical conditions characterized by different psycho-somatic profiles and symptoms. There is also a lack of research that clarify such peculiarities. Vul…

L’endometriosi è una patologia ginecologica cronica caratterizzata dalla presenza e dalla crescita di tessuto endometriale al di fuori dalla cavità uterina. Le cisti sono solitamente localizzate nell’area addominale e nelle zone circostan…

Glanzmann’s thrombasthenia (GT) is a rare bleeding syndrome characterized by deficiency or defect of platelet aggregation complex. The pathogenesis of endometriosis is controversial but the strongest evidence leans towards retrograde menstr…

Introduction: Endometriosis is a chronic disease often associated with pelvic pain and infertility. It has been shown that vitamin D plays an important role in the physiological functions of the reproductive system. Conflicting data have be…