Endometriosis and Glanzmanns thrombasthenia.

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This paper describes three sisters with endometriosis and Glanzmann's thrombasthenia, presenting challenges in managing bleeding risks, particularly during surgical interventions.

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Abstract

Glanzmann’s thrombasthenia (GT) is a rare bleeding syndrome characterized by deficiency or defect of platelet aggregation complex. The pathogenesis of endometriosis is controversial but the strongest evidence leans towards retrograde menstruation. GT probably predisposes to endometriosis. The management of women affected by this disease can be difficult due to the risk of bleeding complications, especially during surgical treatment. We describe the cases of three sisters affected by endometriosis and GT, referred to our Department, who received different therapeutic management.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Thrombasthenia Adult Contraceptives, Oral, Hormonal Contraceptives, Oral, Hormonal Contraceptives, Oral, Hormonal Diseases in Twins Disease Susceptibility Endometriosis Endometriosis Endometriosis Endometriosis Factor VIIa Factor VIIa Female Hematometra Hematometra Hemorrhagic Disorders Hemorrhagic Disorders Hemorrhagic Disorders

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Cited by (2)

Cited by (2)

Source provenance

europepmc
last seen: 2026-09-06T09:34:12.023084+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:20:54.390225+00:00
License: CC0 · commercial use OK