Aim. To determine the clinical, anamnestic, and immunological predictors of adenomyosis by developing a prognostic model of uterine fibroids with concomitant adenomyosis. Materials and methods. A retrospective single-center study was condu…
Objective. To perform comparative analysis of clinical data, serum levels of acute-phase proteins, cytokines, steroid hormones, and expression of genes encoding sex hormone receptors in tissues of patients with proliferative diseases of the…
Treatment efficiency of chronic infertility does not exceed 40% when using in vitro fertilization (IVF) programs. Therefore, sufficient attention should be given to studies of pathogenetic mechanisms, identification and correction of the fa…
Pathogenetic mechanisms of uterine leiomyoma, adenomyosis and their combination are complicated and poorly understood, a differential diagnosis of leiomyosarcoma of the uterus is difficult. Our study aimed for a comparative analysis of the …
We studied blood contents of alpha-2-macroglobulin (α2-MG), pregnancy-associated alpha2-glycoprotein (PAG), and their immune complexes with IgG in healthy female controls, as well as in women with adenomyosis, females with uterine myoma (wi…
Objective — to study the blood levels of some cytokines, vascular endothelial growth factor (VEGF), and their synthesis-modulating lactoferrin (LF) and α 2 -macroglobulin (α 2 -MG) in women with uterine myoma, adenomyosis, and their concurr…
We studies blood sera of the women with verified endometriosis (End), cancer of ovaries (Can), cystadenoma (Cyst) and healthy women by similar age (Cont) for the contents of cytokines (TNFα, IL - 1β, IL-6, IFNγ), some macroglobulin proteins…