Lucy H R Whitaker

No ORCID on file · 14 papers in corpus · active 2014-2025

Study types

  • article 6
  • other 3
  • review 3
  • erratum 1
  • letter 1

Condition tags

  • endometriosis 11
  • mesh:D004715 6
  • chronic_pelvic_pain 4
  • mesh:D017699 2
  • adenomyosis 1
article 2025
Insights into endometriosis symptom trajectories and assessment of surgical intervention outcomes using longitudinal actigraphy
NPJ digital medicine ·doi:10.1038/s41746-025-01629-8

Abstract Endometriosis is a common, chronic condition associated with debilitating pain, fatigue, and heterogeneous symptom presentation. In this exploratory study, 68 participants with confirmed endometriosis were monitored for up to three…

review 2024
Endometriosis: cannabidiol therapy for symptom relief
Trends in pharmacological sciences ·doi:10.1016/j.tips.2024.10.014

Endometriosis is a common, chronic, incurable condition the hallmark of which is the presence of lesions (tissue resembling endometrium) in sites outside the womb, with symptoms including chronic debilitating pain and fatigue. However, curr…

article 2024
Endometriosis: Improvements and challenges in diagnosis and symptom management
Cell reports. Medicine ·doi:10.1016/j.xcrm.2024.101596

Endometriosis is a chronic disorder with debilitating symptoms that is difficult to diagnose and treat. Advances in imaging technologies and strategies for the management of symptoms are improving the quality of life of patients by reducing…

other 2024
Genome-wide association reveals a locus in neuregulin 3 associated with gabapentin efficacy in women with chronic pelvic pain
iScience ·doi:10.1016/j.isci.2024.110370

Chronic pelvic pain (CPP) in women with no obvious pelvic pathology has few evidence-based treatment options. Our recent multicenter randomized controlled trial (GaPP2) in women with CPP and no obvious pelvic pathology showed that gabapenti…

other 2023
Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON): a randomised controlled phase III trial
EClinicalMedicine ·doi:10.1016/j.eclinm.2023.101995

BACKGROUND: Heavy menstrual bleeding affects one in four women and negatively impacts quality of life. Ulipristal acetate is prescribed to treat symptoms associated with uterine fibroids. We compared the effectiveness of ulipristal acetate …

article 2022
Endometriosis
BMJ (Clinical research ed.) ·doi:10.1136/bmj-2021-068950
other 2021
Laparoscopic treatment of isolated superficial peritoneal endometriosis for managing chronic pelvic pain in women: study protocol for a randomised controlled feasibility trial (ESPriT1)
Pilot and feasibility studies ·doi:10.1186/s40814-020-00740-9

BACKGROUND: Endometriosis (where endometrial-like tissue is found outside the uterus) affects ~ 176 million women worldwide and can lead to debilitating pelvic pain. Three subtypes of endometriosis exist, with ~ 80% of women having superfic…

review 2021
Menstruation Dysregulation and Endometriosis Development
Frontiers in reproductive health ·doi:10.3389/frph.2021.756704

Endometriosis is a common gynecological condition characterized by the growth of endometrial-like tissue outside of the uterus which may cause symptoms such as chronic pelvic pain or subfertility. Several surgical and medical therapies are …

article 2021
The endometrial response to modulation of ligand-progesterone receptor pathways is reversible
Fertility and sterility ·doi:10.1016/j.fertnstert.2021.02.008

ObjectiveTo study the impact of the progesterone receptor modulator (PRM), ulipristal acetate (UPA), on endometrial morphology and function.DesignCross-sectional.SettingUniversity Research Institute.Patient(s)Endometrial biopsies from 16 pa…

article 2020
A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1)
PloS one ·doi:10.1371/journal.pone.0227695

BACKGROUND: Endometriosis is defined by the presence of endometrial-like tissue (lesions) outside the uterus, commonly on the pelvic peritoneum. It affects 6-10% of women and is associated with debilitating pelvic pain. Current management o…

erratum 2020
Correction: A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1)
PloS one ·doi:10.1371/journal.pone.0230055

[This corrects the article DOI: 10.1371/journal.pone.0227695.].

letter 2019
Proposal for a new ICD-11 coding classification system for endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2019.08.015
article 2016
An Exploratory Study into Objective and Reported Characteristics of Neuropathic Pain in Women with Chronic Pelvic Pain
PloS one ·doi:10.1371/journal.pone.0151950

Chronic pelvic pain (CPP) affects 5.7-26.6% women worldwide. 55% have no obvious pathology and 40% have associated endometriosis. Neuropathic pain (NeP) is pain arising as a consequence of a lesion/disease affecting the somatosensory system…

review 2014
Selective progesterone receptor modulators
Current opinion in obstetrics & gynecology ·doi:10.1097/GCO.0000000000000082

PURPOSE OF REVIEW: Review of recent data from clinical trials and descriptions of endometrial morphology with administration of selective progesterone receptor modulators (SPRMs). RECENT FINDINGS: Recent reports concerning administration o…