Fiona C. Denison

ORCID: 0000-0003-0371-2014 · 6 papers in corpus
article 2020
A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1)
PloS one ·doi:10.1371/journal.pone.0227695

BACKGROUND: Endometriosis is defined by the presence of endometrial-like tissue (lesions) outside the uterus, commonly on the pelvic peritoneum. It affects 6-10% of women and is associated with debilitating pelvic pain. Current management o…

erratum 2020
Correction: A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1)
PloS one ·doi:10.1371/journal.pone.0230055

[This corrects the article DOI: 10.1371/journal.pone.0227695.].

article 2018
A pilot randomised double blind controlled trial of the efficacy of purified fatty acids for the treatment of women with endometriosis-associated pain (PurFECT): study protocol
Pilot and feasibility studies ·doi:10.1186/s40814-018-0274-8

BACKGROUND: Endometriosis affects 6-10% of women and is associated with debilitating pelvic pain. It costs the UK > £2.8 billion per year in loss of productivity. Endometriosis can be managed by surgical excision or medically by ovarian sup…

2011
A role for lipoxin A₄ as an anti-inflammatory mediator in the human endometrium.
Reproduction (Cambridge, England) ·doi:10.1530/rep-11-0021

Lipoxin A(4) is a lipid mediator that elicits anti-inflammatory and pro-resolution actions via its receptor, formyl peptide receptor 2 (FPR2/ALX). In this study, we aimed to investigate the expression and potential role of lipoxin A(4) and …

2011
CTGF expression is up-regulated by PROK1 in early pregnancy and influences HTR-8/Svneo cell adhesion and network formation.
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deq294

BackgroundProkineticin-1 (PROK1) and connective tissue growth factor (CTGF) are expressed in human endometrium and first-trimester decidua and have individually been proposed to have roles in implantation and placentation. We have recently …

2010
Evidence of prokineticin dysregulation in fallopian tube from women with ectopic pregnancy.
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.10.061

ObjectiveTo demonstrate expression and regulation of prokineticins (PROKs) and their receptors (PROKRs) in fallopian tube (FT) from women who are not pregnant and women with ectopic pregnancy (EP).DesignTissue analysis.SettingLarge United K…