Ying Wang

BACKGROUND: For patients with severe endometriosis, the spontaneous pregnancy rates have been reported to be near 0 due to extreme distortion of normal pelvic anatomy. Surgery is one of the treatment options; however, if patients failed to …

Objective:To study the expression and functionofvascularendothelialgrowthfactor(VEGF) inendometriosis(EMs) andVEGF in the occurrence of endometriosis development. Methods: The VEGF expression from 36 cases of ectopic endometrium,36 cases of…

OBJECTIVE: To study the inhibitory effect on estradiol (E2) production of endometriosis by medicated serum of Jiawei Sanleng pill (SLW) and approach the mechanism of inducing apoptosis of human endometrial cells of endometriosis by medicate…

OBJECTIVE: To study the inhibitory effect of medicated serum of SLW on estrogen production and to approach on the key mechanism of SLW in inhibiting the invasion ability of endometrial cells of endometriosis. METHOD: First, the model of eu…

OBJECTIVE To investigate the difference in expression of aromatase and cyclooxygenase-2 in human eutopic endometrial cells derived from endometriosis and hysteromyoma and to explore the effect of medicated serum of SLW on aromatase and cycl…

OBJECTIVE: To explore the effect mechanism of Sanlengwan (SLW) on estrogen production in ectopic endometrium of rats. METHOD: The rat model of endometriosis was established by surgical implant of endometrial tissue which belong to its body.…

OBJECTIVE: To investigate the association of the matrix metalloproteinases (MMP) 1, 3 promoter single nucleotide polymorphism (SNP) with the susceptibility to endometriosis (EM) and adenomyosis. METHODS: The SNP of the MMP-1 and MMP-3 gene …

目的 探讨基质金属蛋白酶(MMP)1、 3启动子区基因多态性与子宫内膜异位症和子宫腺肌病遗传易感性的相关性.方法采用聚合酶链反应限制性片段长度多态性(PCR-RFLP)方法,分析100例子宫内膜异位症患者(内异症组)、 80例子宫腺肌病组患者(腺肌病组)和150例健康妇女(对照组)MMP-1和MMP-3基因型及等位基因频率分布.结果 (1)MMP-1中2G等位基因频率在内异症组和腺肌病组患者中分别为79.0%(158/200)和79.4%(127/160),明显高于对照组(6…

Fifteen cases of endometriosis were treated with method of warming and dispelling kidney.The blood TNF α and IL 8 before and after treatment were determined.Result:Before treatment,blood TNF α and IL 8 were significantly higher than the nor…