Robert J. D’Amato

No ORCID on file · 9 papers in corpus · active 2005-2015

Study types

  • article 8
  • review 1

Condition tags

  • endometriosis 9
  • infertility 2
article 2015
The FASEB Journal • Research Communication Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis

ABSTRACT Endometriosis affects 10–15 % of women and is associated with pelvic pain and infertility. Angio-genesis plays an essential role in its pathogenesis. Den-dritic cells (DCs) were recently implicated in supporting tumor angiogenesis.…

article 2013
Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis
Angiogenesis ·doi:10.1007/s10456-013-9333-1

Endometriosis is an angiogenesis-dependent disease. Many studies demonstrated inhibition of angiogenesis leads to inhibition of endometriotic growth, however underlying mechanism is still not fully understood. Our previous study suggested v…

article 2011
Circulating Endothelial Progenitor Cells Are Up-Regulated in a Mouse Model of Endometriosis
The American journal of pathology ·doi:10.1016/j.ajpath.2010.12.037

Endometriosis is a debilitating disease characterized by the growth of ectopic endometrial tissue. It is widely accepted that angiogenesis plays an integral part in the establishment and growth of endometriotic lesions. Recent data from a v…

review 2007
Angiogenesis and antiangiogenic therapy in endometriosis
Microvascular research ·doi:10.1016/j.mvr.2007.04.008

Endometriosis, the presence of endometrium-like tissue outside of the uterine cavity, is a common disease among women of reproductive age. Typical symptoms include abdominal pain and painful menstruation. In addition, endometriosis is assoc…

article 2007
Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.07-9034com

Endometriosis affects 10-15% of women and is associated with pelvic pain and infertility. Angiogenesis plays an essential role in its pathogenesis. Dendritic cells (DCs) were recently implicated in supporting tumor angiogenesis. As both tum…

article 2006
A Novel Noninvasive Model of Endometriosis for Monitoring the Efficacy of Antiangiogenic Therapy
The American journal of pathology ·doi:10.2353/ajpath.2006.051133

Endometriosis, the presence of ectopic endometrial tissue, is a common disease associated with high morbidity and socioeconomic problems. Angiogenesis, the formation of new blood vessels, plays an important role in the formation and growth …

article 2006
Short synthetic endostatin peptides inhibit endothelial migration in vitro and endometriosis in a mouse model
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.07.1290

ObjectiveTo determine the active peptide regions inside the angiogenesis inhibitor endostatin that can inhibit endothelial migration in vitro and also inhibit endometriosis in a mouse model.DesignPharmacologic intervention in a surgically i…

article 2005
Endostatin inhibits the growth of endometriotic lesions but does not affect fertility
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.04.040

ObjectiveTo determine whether endometriosis can be treated with the angiogenesis inhibitor endostatin and the effect of this treatment on fertility and reproduction.DesignPharmacologic intervention in a surgically induced model of endometri…

article 2005
Nonsteroidal antiinflammatory drugs differentially suppress endometriosis in a murine model
Fertility and Sterility ·doi:10.1016/j.fertnstert.2004.06.058

ObjectiveTo determine whether nonsteroidal antiinflammatory drugs (NSAIDs) affect the establishment and progression of endometriotic lesions in a murine model.DesignPharmacologic intervention in a surgically induced murine model of abdomina…