Isao Tamura

No ORCID on file · 9 papers in corpus · active 2010-2026

Study types

  • article 5
  • other 2
  • dataset 1
  • rct 1

Condition tags

  • endometriosis 6
  • endometrioma 4
  • infertility 2
other 2026
Establishment of a xenograft model of endometriosis-associated fibrosis using human immortalized endometrial stromal cells overexpressing HOXC8
Scientific reports ·doi:10.1038/s41598-026-41956-8

Endometriosis is a disease characterized by fibrosis and adhesions. There are still no treatment methods targeting these conditions. One reason for this is the lack of useful animal models to investigate the mechanisms of fibrosis and adhes…

article 2023
Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas
Reproductive medicine and biology ·doi:10.1002/rmb2.12548

Purpose: To test the theory that invaginated ovarian surface epithelium and endometrial implants on the ovary form ovarian endometriomas. Methods: Adhesion sites of ovarian endometrioma on the peritoneum and consecutive ovarian endometrioma…

dataset 2020
An integrated genomic approach identifies HOXC8 as an upstream regulator in ovarian endometrioma
·doi:10.5061/dryad.s4mw6m94g

Purpose: To identify the upstream regulators (URs) involved in the onset and pathogenesis of ovarian endometrioma. Methods: Recently, a method called SMITE that uses transcriptome data in combination with publicly available data for identif…

article 2020
An Integrated Genomic Approach Identifies HOXC8 as an Upstream Regulator in Ovarian Endometrioma
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgaa618

PURPOSE: To identify the upstream regulators (URs) involved in the onset and pathogenesis of ovarian endometrioma. METHODS: Recently, a method called Significance-based Modules Integrating the Transcriptome and Epigenome (SMITE) that uses t…

other 2019
Aberrant DNA methylation suppresses expression of estrogen receptor 1 (ESR1) in ovarian endometrioma
Journal of ovarian research ·doi:10.1186/s13048-019-0489-1

BACKGROUND: In ovarian endometriomas (OE), the expression statuses of various steroid hormone receptors are altered compared with their expression statuses in eutopic endometrium (EE). For example, in OE, the expressions of estrogen recepto…

rct 2019
The clinical outcome of Dienogest treatment followed by in vitro fertilization and embryo transfer in infertile women with endometriosis
Journal of ovarian research ·doi:10.1186/s13048-019-0597-y

BACKGROUND: Endometriosis is considered to be the most intractable cause of female infertility. Administering any type of treatment for endometriosis before in vitro fertilization and embryo transfer (IVF-ET) is an important strategy for im…

article 2011
POSTER VIEWING SESSION - ENDOMETRIOSIS, ENDOMETRIUM, IMPLANTATION AND FALLOPIAN TUBE
·doi:10.1093/humrep/26.s1.80
article 2010
Posters * Endometriosis, Endometrium and Implantation
·doi:10.1093/humrep/de.25.s1.242

Introduction: Endometriosis, defined as the growth of endometrial tissue outside \nthe uterine cavity is a common gynaecological disorder affecting 10-15% \nof women in their reproductive years. It is a major clinical problem causing in- \n…

article 2010
Progesterone Increases Manganese Superoxide Dismutase Expression via a cAMP-Dependent Signaling Mediated by Noncanonical Wnt5a Pathway in Human Endometrial Stromal Cells
·doi:10.1210/mend.24.9.9997

Patients and Methods: Endometrial tissues were collected from women with regular menstrual cycles; tissues were used for recovery of primary ESC or RNA extraction or were fixed for immunohistochemistry. Primary ESC were decidualized in vitr…