Omwandho COA

No ORCID on file · 9 papers in corpus · active 2018-2024

Study types

  • article 6
  • review 2
  • preprint 1

Condition tags

  • endometriosis 9
  • adenomyosis 2
  • thoracic_endometriosis 1
  • die_deep_infiltrating 1
review 2024
Biomedicines ·doi:10.3390/biomedicines12061276

The changes in endometrial cells, both in the eutopic endometrium of patients with and without endometriosis and in lesions at ectopic sites, are frequently described and often compared to tumorigenesis. In tumorigenesis, the concept of "se…

article 2023
Biomedicines ·doi:10.3390/biomedicines11102730

BACKGROUND: Membrane type-matrix metalloproteinases (MT-MMPs) are a subgroup of the matrix metalloproteinases (MMPs) family and are key molecules in the degradation of the extracellular matrix. Membrane type-1 matrix metalloproteinase (MT1-…

preprint 2023
·doi:10.20944/preprints202306.0009.v1

In the pathogenesis of endometriosis, the differences between the eutopic and ectopic endometrium as well as between the eutopic endometrium with and without endometriosis are repeatedly pointed out. Various mechanisms have been suggested t…

article 2022
Biomolecules ·doi:10.3390/biom12121749

The TGF-β superfamily members, activins and inhibins, are mainly involved in cell proliferation, cell survival, invasion, immune surveillance, and lesion growth in endometriosis. Herein, we investigated the modulation of the TGF-β type III …

article 2022
Diagnostics ·doi:10.3390/diagnostics12040779

Matrix metalloproteinases (MMPs) play an important role in menstruation and endometriosis; however, the membrane-type matrix metalloproteinases (MT-MMPs) are not well studied in endometriosis and adenomyosis. We analyzed MT2-MMP (MMP15) and…

article 2022
Biology ·doi:10.3390/biology11040513

Endometriosis is characterized by the presence of ectopic endometrium most often in the pelvis. The transforming growth factor-beta (TGF-β) superfamily is also involved in the pathogenesis; however, betaglycan (BG, syn. TGF-β type III recep…

review 2021
Cells ·doi:10.3390/cells10010180

Thoracic endometriosis (TE) is a rare type of endometriosis, where endometrial tissue is found in or around the lungs and is frequent among extra-pelvic endometriosis patients. Catamenial pneumothorax (CP) is the most common form of TE and …

article 2019
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2019.11.007

Research questionHow closely related are adenomyotic and endometrial glands?DesignIn this study, the mRNA and protein database www.proteinatlas.org was searched for proteins expressed predominantly in the endometrial glands. Specificity was…

article 2018
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118756745

Epithelial-mesenchymal transition (EMT) is characterized by the loss of epithelial and acquisition of mesenchymal cell characteristics. Our aim was to assess the epithelial phenotype in the pathogenesis of endometriosis with epithelial and …