Yan Liu

R eview question / Objective The review aims to identify risk factors associated with recurrence of endometriosis and pregnancy gain after surgery.P: Ovarian endometriosis patients after surgery I: No artificial intervention C:Patients with…

BACKGROUND: This study evaluated the effectiveness of quinagolide vaginal ring on reducing total lesion size in endometrioma, deep infiltrating endometriosis (DIE), and adenomyosis, as assessed using high-resolution MRI and imaging biomarke…

RATIONALE: Spontaneous uterine rupture, although rare, is a life-threatening obstetric emergency with a high maternal and fetal mortality rate. It can occur without warning, leading to severe complications, including hemorrhage, shock, and …

BACKGROUND: An increasing body of observational studies have indicated an association between gut microbiota and endometriosis. However, the causal relationship between them is not yet clear. In this study, we employed Mendelian randomizati…

It is well known that the transfer of embryos at the blastocyst stage is superior to the transfer of embryos at the cleavage stage in many respects. However, the rate of blastocyst formation remains low in clinical practice. To reduce the p…

Endometriosis of sciatic nerve is a common gynecological disease. Here we aimed to study the anti-inflammatory and anti-nociceptive role of sulforaphane on sciatic nerve endometriosis. The sciatic nerve endometriosis rat model was construct…

ObjectiveTo explore the possible mechanism of protein kinase CK2, which participates in estrogen recruitment of endothelial progenitor cells (EPCs), and its role in the angiogenesis of endometriosis lesions.DesignLaboratory study.SettingUni…

This study investigated the relationship between the pain of sciatic endometriosis and the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathway. Adult female Sprague-Dawley rats succ…

This retrospective analysis aimed to clarify the clinical and pathologic features of ovarian clear cell carcinoma (OCCC), and to determine the factors predictive of survival.Data waereextracted from OCCC patients who underwent primary surge…

Endometriosis is one of the most common diseases in women. Inflammation and angiogenesis have been shown to be important in pathogenesis of endometriosis. Crocin is known as an anti-inflammatory, anti- proliferation substance. This study wa…

BACKGROUND: Considered as the precursor lesion of a subset of ovarian clear cell carcinoma (OCCC), the prognostic role of endometriosis in OCCC patients remains controversial. This study aimed to investigate the prognostic role of coexistin…

To investigate the effects and the underlying mechanisms of ginsenoside Rf in a surgically induced rat endometriosis model, endometriosis was constructed through homologous transplantation and the Wistar rats were further randomly classifie…

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin growth factors family. Recent studies indicated that the level of BDNF in follicular fluid is a marker for oocyte quality and infertility. Here, we intend to further i…

Endomorphin-1 (EM-1) was reported to have very high affinity and selectivity for μ-opioid receptor (MOR). However, it remained unclear whether EM-1 and MOR were involved in the pathologies of endometriosis resulting in reduced fertility. In…

Objective To investigate the Ang-2,the relationship between VEGF and angiogenesis and its expression in ovarian endometriosis(EMs).Methods Selected at between 2007.1-2011.12 collection of ovarian endometriosis patients with surgical specime…

ObjectiveTo evaluate the effect of carbon dioxide (CO2) pneumoperitonal pressure on the ultrastructure of implanted endometriotic lesions in a rat model.Study designAn endometriotic model was established in Sprague-Dawley rats with peritone…

Objective:To explore the expression of proliferation cell nuclear antigen ki-67 in endometriosis and the effect of proliferative activity of endometrial cells on the occurrence of endometriosis.Methods:Immunohistochemical SP method was used…

Objective:To detect the expression of anti-apoptosis Survivin and Bcl-2 in endometriosis,and to explore the role of apoptosis in the pathogenesis of endometriosis. Methods:The expression of Survivin and Bcl-2 were detected by EnVision metho…

OBJECTIVE To investigate the mifepristone's clinical application in adenomyosis of uterus during the peri-menopausal period and seek for effective,less-complicational,acceptable ways to improve the quality of life.METHODS 64 cases were stud…

Endometriosis is a poorly understood, estradiol-dependent condition associated with severe pelvic pains and defined by vascularized endometrial growths outside the uterus. Endometriosis is produced in cycling rats by autotransplanting piece…